Author
Muni Kumar Meravath is a seasoned Healthcare Market Research Analyst with over 6 years of experience in the healthc.....
Bone Substitute And Allografts Bone Market: By Products, Bone Grafts Substitutes and Synthetic Bone Grafts), and Cell-Based Matrices)), By Application and By Geography
The bone substitute and allograft bone market size was valued at US$ 3.1 billion in 2022 and growing at a CAGR of 6.1% from 2023 to 2029. The growing use of grafts in dental operations is expected to generate profitable growth prospects for the market players during the forecast period. Rising demand for dental bone grafts and technological advances propel the market forward. Increased investment in R&D by key players in bone grafts and their substitutes and an increase in incidences of orthopedic operations among the elderly are projected to generate significant growth for market players over the forecast period. Introducing novel polymer and ceramic materials with biologically superior features is one of the market's essential developments.
New manufacturing technologies like fast prototyping and 3D printing assist in the manufacture of free-form biomaterial scaffolds for tissue regeneration. Furthermore, increased morbidity rates, a growing geriatric population, and an increase in occurrences of osteoarthritis are driving up demand for bone grafts and substitutes. Apart from that, the market is being bolstered by a shift toward minimally invasive procedures and a growing awareness among patients about the benefits of biologic bone regeneration. The availability of improved products in various forms and sizes, the rising frequency of orthopedic difficulties and periodontal disorders, and the growing number of studies examining the enhancement of bioactivity of bone graft substitutes are some of the other growth-inducing aspects.
To maintain the market position in the competition, key players worldwide employ various techniques in the bone graft substitutes market. Companies are concentrating on launching sophisticated products and strengthening their distribution channels. Moreover, numerous companies in the global bone graft replacements market are investing in research to develop high-efficiency materials. For instance, in January 2021, Dentsply Sirona acquired Datum Dental Ltd., a company recognized for its unique dental regeneration solutions. Dentsply Sirona promotes the whole OSSIX portfolio in the United States, Canada, and several other countries, including OSSIX Plus, OSSIX Volumax, and OSSIX Bone.
Study Period
2024-2030Base Year
2023CAGR
6.1%Largest Market
EuropeFastest Growing Market
Asia-Pacific
The development of biocompatible synthetic bone grafts, technical improvements for adopting allografts from autografts, and increased demand for dental bone transplants drive the global bone grafts and substitutes market. Bone graft substitutes are gaining popularity as bone graft extenders, particularly posterolateral spinal fusion. As a result, bone graft substitutes for spine fusion procedures have increased dramatically. The worldwide market is predicted to see significant growth due to an increase in spine fusion surgeries. However, higher surgical costs and ethical concerns about bone grafting operations are expected to hinder market expansion for bone grafts and alternatives.
Report Benchmarks |
Details |
Report Study Period |
2024-2030 |
Market Size in 2022 |
US$ 3.1 billion |
Market CAGR |
6.1% |
By Product Type |
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By Application |
|
By Region |
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The bone substitutes and bone allografts market is projected to expand at a CAGR of 6.1% during the forecast period.
Medtronic, Stryker Corporation, Smith and Nephew Inc, NuVasive, Inc., Wright Medical Group N.V
North America is the fastest-growing region for bone substitutes and the bone allografts market
1. Executive Summary |
2. Global Bone Substitutes and Bone Allografts Market Introduction |
2.1. Global Bone Substitutes and Bone Allografts Market Taxonomy |
2.2. Global Bone Substitutes and Bone Allografts Market Definitions |
2.2.1. Product |
2.2.2. Application |
3. Global Bone Substitutes and Bone Allografts Market Dynamics |
3.1. Drivers |
3.2. Restraints |
3.3. Opportunities/Unmet Needs of the Market |
3.4. Trends |
3.5. Global Bone Substitutes and Bone Allografts Market Dynamic Factors - Impact Analysis |
3.6. Global Bone Substitutes and Bone Allografts Market Competition Landscape |
4. Global Bone Substitutes and Bone Allografts Market Analysis,2018 - 2022 and Forecast, 2023 - 2029 |
4.1. Market Analysis,2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) |
4.3. Market Opportunity Analysis |
5. Global Bone Substitutes and Bone Allografts Market, By Product, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.1. Bone Substitutes |
5.1.1. Hydroxyapatites (HAp) |
5.1.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.1.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.1.1.3. Market Opportunity Analysis |
5.1.2. Calcium Phosphate |
5.1.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.1.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.1.2.3. Market Opportunity Analysis |
5.1.3. Calcium Sulphate |
5.1.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.1.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.1.3.3. Market Opportunity Analysis |
5.1.4. Bioactive Glass |
5.1.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.1.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.1.4.3. Market Opportunity Analysis |
5.2. Bone Allografts |
5.2.1. Freeze Dried |
5.2.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.2.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.2.1.3. Market Opportunity Analysis |
5.2.2. Demineralized Bone Matrix |
5.2.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.2.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.2.2.3. Market Opportunity Analysis |
5.2.3. Tendon Allografts |
5.2.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.2.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.2.3.3. Market Opportunity Analysis |
5.2.4. Synthetic Tendon Grafts |
5.2.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
5.2.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.2.4.3. Market Opportunity Analysis |
6. Global Bone Substitutes and Bone Allografts Market, By Application, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.1. Spinal Fusion |
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.1.3. Market Opportunity Analysis |
6.2. Long Bone |
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.2.3. Market Opportunity Analysis |
6.3. Foot and Ankle |
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.3.3. Market Opportunity Analysis |
6.4. Craniomaxillofacial |
6.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.4.3. Market Opportunity Analysis |
6.5. Joint Reconstruction |
6.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.5.3. Market Opportunity Analysis |
6.6. Dental Bone Grafting |
6.6.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.6.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.6.3. Market Opportunity Analysis |
6.7. Others |
6.7.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
6.7.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.7.3. Market Opportunity Analysis |
7. Global Bone Substitutes and Bone Allografts Market Forecast, By Region, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.1. North America |
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.1.3. Market Opportunity Analysis |
7.2. Europe |
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.2.3. Market Opportunity Analysis |
7.3. Asia-Pacific |
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.3.3. Market Opportunity Analysis |
7.4. Latin America |
7.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.4.3. Market Opportunity Analysis |
7.5. Middle East and Africa |
7.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
7.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.5.3. Market Opportunity Analysis |
7.6. Global Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application and Region, 2023 - 2029 |
8. North America Bone Substitutes and Bone Allografts MarketAnalysis,2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
8.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%) |
8.1.1. Bone Substitutes |
8.1.1.1. Hydroxyapatites (HAp) |
8.1.1.2. Calcium Phosphate |
8.1.1.3. Calcium Sulphate |
8.1.1.4. Bioactive Glass |
8.1.2. Bone Allografts |
8.1.2.1. Freeze Dried |
8.1.2.2. Demineralized Bone Matrix |
8.1.2.3. Tendon Allografts |
8.1.2.4. Synthetic Tendon Grafts |
8.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
8.2.1.1. Spinal Fusion |
8.2.1.2. Long Bone |
8.2.1.3. Foot and Ankle |
8.2.1.4. Craniomaxillofacial |
8.2.1.5. Joint Reconstruction |
8.2.1.6. Dental Bone Grafting |
8.2.1.7. Others |
8.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
8.3.1. USA |
8.3.2. Canada |
8.4. North America Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application, and Country, 2023 - 2029 |
8.5. North America Bone Substitutes and Bone Allografts Market Dynamics Trends |
9. Europe Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
9.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%) |
9.1.1. Bone Substitutes |
9.1.1.1. Hydroxyapatites (HAp) |
9.1.1.2. Calcium Phosphate |
9.1.1.3. Calcium Sulphate |
9.1.1.4. Bioactive Glass |
9.1.2. Bone Allografts |
9.1.2.1. Freeze Dried |
9.1.2.2. Demineralized Bone Matrix |
9.1.2.3. Tendon Allografts |
9.1.2.4. Synthetic Tendon Grafts |
9.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
9.2.1.1. Spinal Fusion |
9.2.1.2. Long Bone |
9.2.1.3. Foot and Ankle |
9.2.1.4. Craniomaxillofacial |
9.2.1.5. Joint Reconstruction |
9.2.1.6. Dental Bone Grafting |
9.2.1.7. Others |
9.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
9.3.1. Germany |
9.3.2. UK |
9.3.3. France |
9.3.4. Spain |
9.3.5. Italy |
9.3.6. Russia |
9.3.7. Poland |
9.3.8. Rest of Europe |
9.4. Europe Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application, and Country, 2023 - 2029 |
9.5. Europe Bone Substitutes and Bone Allografts Market Dynamics Trends |
10. Asia-Pacific Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
10.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%) |
10.1.1. Bone Substitutes |
10.1.1.1. Hydroxyapatites (HAp) |
10.1.1.2. Calcium Phosphate |
10.1.1.3. Calcium Sulphate |
10.1.1.4. Bioactive Glass |
10.1.2. Bone Allografts |
10.1.2.1. Freeze Dried |
10.1.2.2. Demineralized Bone Matrix |
10.1.2.3. Tendon Allografts |
10.1.2.4. Synthetic Tendon Grafts |
10.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
10.2.1.1. Spinal Fusion |
10.2.1.2. Long Bone |
10.2.1.3. Foot and Ankle |
10.2.1.4. Craniomaxillofacial |
10.2.1.5. Joint Reconstruction |
10.2.1.6. Dental Bone Grafting |
10.2.1.7. Others |
10.3. Country Analysis2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
10.3.1. Japan |
10.3.2. China |
10.3.3. India |
10.3.4. ASEAN |
10.3.5. Australia & New Zealand |
10.3.6. Rest of Asia-Pacific |
10.4. Asia-Pacific Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application, and Country, 2023 - 2029 |
10.5. Asia-Pacific Bone Substitutes and Bone Allografts Market Dynamics Trends |
11. Latin America Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
11.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%) |
11.1.1. Bone Substitutes |
11.1.1.1. Hydroxyapatites (HAp) |
11.1.1.2. Calcium Phosphate |
11.1.1.3. Calcium Sulphate |
11.1.1.4. Bioactive Glass |
11.1.2. Bone Allografts |
11.1.2.1. Freeze Dried |
11.1.2.2. Demineralized Bone Matrix |
11.1.2.3. Tendon Allografts |
11.1.2.4. Synthetic Tendon Grafts |
11.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
11.2.1.1. Spinal Fusion |
11.2.1.2. Long Bone |
11.2.1.3. Foot and Ankle |
11.2.1.4. Craniomaxillofacial |
11.2.1.5. Joint Reconstruction |
11.2.1.6. Dental Bone Grafting |
11.2.1.7. Others |
11.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
11.3.1. Brazil |
11.3.2. Mexico |
11.3.3. Argentina |
11.3.4. Rest of Latin America |
11.4. Latin America Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application, and Country, 2023 - 2029 |
11.5. Latin America Bone Substitutes and Bone Allografts Market Dynamics Trends |
12. Middle East and Africa Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn) |
12.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%) |
12.1.1. Bone Substitutes |
12.1.1.1. Hydroxyapatites (HAp) |
12.1.1.2. Calcium Phosphate |
12.1.1.3. Calcium Sulphate |
12.1.1.4. Bioactive Glass |
12.1.2. Bone Allografts |
12.1.2.1. Freeze Dried |
12.1.2.2. Demineralized Bone Matrix |
12.1.2.3. Tendon Allografts |
12.1.2.4. Synthetic Tendon Grafts |
12.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
12.2.1.1. Spinal Fusion |
12.2.1.2. Long Bone |
12.2.1.3. Foot and Ankle |
12.2.1.4. Craniomaxillofacial |
12.2.1.5. Joint Reconstruction |
12.2.1.6. Dental Bone Grafting |
12.2.1.7. Others |
12.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
12.3.1. Gulf Cooperation Council (GCC) Countries |
12.3.2. Israel |
12.3.3. South Africa |
12.3.4. Rest of MEA |
12.4. MEA Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application, and Country, 2023 - 2029 |
12.5. MEA Bone Substitutes and Bone Allografts Market Dynamics Trends |
13. Competition Landscape |
13.1. Strategic Dashboard of Top Market Players |
13.2. Company Profiles (Introduction, Financial Analysis, Technology & Service Offerings, Key Developments, Strategies, and SWOT Analysis) |
13.2.1. AlloSource |
13.2.2. Baxter |
13.2.3. DEPUY SYNTHES |
13.2.4. INTEGRA LIFESCIENCES HOLDINGS CORPORATION |
13.2.5. Medtronic |
13.2.6. NuVasive, Inc. |
13.2.7. Orthovita, Inc. |
13.2.8. Smith and Nephew Inc. |
13.2.9. Stryker Corporation |
13.2.10. Wright Medical Group N.V |
13.2.11. ZIMMER BIOMET |
14. Research Methodology |
15. Key Assumptions and Acronyms |
Key Market Players