Bone Substitutes and Allografts Bone Market: Global Market Size, Dynamics, Regional Share, Trends, Competitor Analysis 2017 to 2021 and Forecast 2022 to 2028

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Bone Substitute And Allografts Bone Market By Products (Allografts (Machined Allografts and Demineralized Bone Matrix), Bone Grafts Substitutes (Bone Morphogenic Proteins (BMP) and Synthetic Bone Grafts), and Cell-Based Matrices)), By Application (Craniomaxillofacial, Dental, Foot & Ankle, Joint Reconstruction, Long Bone, and Spinal Fusion) and Geography

 

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Report

Description

The bone substitute and allograft bone market is valued at USD 3.1 billion in 2021 and is poised to grow at a significant CAGR of 6.1% over 2022–2028. The growing use of grafts in dental operations is expected to generate profitable growth prospects for the market players during the forecast period. Rising demand for dental bone grafts and technological advances propel the market forward. Increased investment in R&D by key players in bone grafts and their substitutes and an increase in incidences of orthopedic operations among the elderly are projected to generate significant growth for market players over the forecast period. Introducing novel polymer and ceramic materials with biologically superior features is one of the market’s essential developments. New manufacturing technologies like fast prototyping and 3D printing assist in the manufacture of free-form biomaterial scaffolds for tissue regeneration. Furthermore, increased morbidity rates, a growing geriatric population, and an increase in occurrences of osteoarthritis are driving up demand for bone grafts and substitutes. Apart from that, the market is being bolstered by a shift toward minimally invasive procedures and a growing awareness among patients about the benefits of biologic bone regeneration. The availability of improved products in various forms and sizes, the rising frequency of orthopedic difficulties and periodontal disorders, and the growing number of studies examining the enhancement of bioactivity of bone graft substitutes are some of the other growth-inducing aspects. To maintain the market position in the competition, key players worldwide employ various techniques in the bone graft substitutes market. Companies are concentrating on launching sophisticated products and strengthening their distribution channels. Moreover, numerous companies in the global bone graft replacements market are investing in research to develop high-efficiency materials. For instance, in January 2021, Dentsply Sirona acquired Datum Dental Ltd., a company recognized for its unique dental regeneration solutions. Dentsply Sirona promotes the whole OSSIX portfolio in the United States, Canada, and several other countries, including OSSIX Plus, OSSIX Volumax, and OSSIX Bone.

Recent Market Developments:

In January 2020, Orthopeaditrics Corp. introduced a synthetic bone graft substitute in the United States called QuickPack. It is highly viscous and contains calcium phosphate cement that closely resembles the mineral phase of a bone.

In March 2022, Fredun Pharmaceuticals Limited received approval to manufacture Xenografts for various dental and orthopedic surgical appliances from the Central Drugs Standard Control Organisation (COSCO), India.

Bone Substitutes And Bone Allografts Market

MARKET SUMMARY
-
6.1% CAGR
  • Study Period– 2022 – 2028
  • Base Year– 2021
  • CAGR– 6.1%
  • Largest Market– Europe
  • Fastest Growing Market– Asia-Pacific

Bone Substitutes And Bone Allografts Market

  • The bone substitutes and bone allografts market report gives comprehensive outlook across the region with special emphasis on key regions such as North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • The bone substitutes and bone allografts market is segmented based on product, application, and geography.
  • Key stakeholders of the bone substitutes and bone allografts market report include suppliers, manufacturers, marketers, policy makers, and healthcare service providers engaged in bone substitutes and bone allografts usage or advocacy.
Key Players
  • Medtronic
  • Stryker Corporation
  • Smith and Nephew Inc
  • NuVasive, Inc.
  • Wright Medical Group N.V
Bone Substitutes And Bone Allografts Market

Dynamics

The development of biocompatible synthetic bone grafts, technical improvements for adopting allografts from autografts, and increased demand for dental bone transplants drive the global bone grafts and substitutes market. Bone graft substitutes are gaining popularity as bone graft extenders, particularly posterolateral spinal fusion. As a result, bone graft substitutes for spine fusion procedures have increased dramatically. The worldwide market is predicted to see significant growth due to an increase in spine fusion surgeries. However, higher surgical costs and ethical concerns about bone grafting operations are expected to hinder market expansion for bone grafts and alternatives.


Europe Got Significant Share

Bone Substitutes And Bone Allografts Market

The bone substitute and allograft bone market in Europe is likely to hold a significant revenue share in 2022, and, in the following years, it is predicted to increase rapidly. The primary factors driving the Europe market growth are growing awareness of commercially available innovative products, the availability of a well-developed healthcare framework, and a 16.9% increase in healthcare expenditure in 2018. Because of the rising number of trauma-related injuries and occurrences of orthopedic disease, the US market is leading the North American and global markets by producing the highest demand for bone grafts and substitutes. During the forecast period, Asia Pacific is expected to grow strongly. Medical tourism, as well as practical government measures, drives the market in the Asia Pacific region.

Latin America
Latin-America
North-America
North-America
Europe
Europe
Asia Pacific
Asia-Pacific
Middle East
Middle East

Key

Features Of the Report

  • The report provides granular level information about the market size, regional market share, historic market (2016-2021), and forecast (2022-2028)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario
Bone Substitutes And Bone Allografts Market Segmentation


Location

GEOGRAPHY

Frequently Asked Questions

2021 is the base year and 2028 is the forecast year.

The report covers the five regions and 15+ countries market data: North America (United States, Canada), Europe (Germany, France, Italy, Spain, and United Kingdom (UK), Asia Pacific (China, India, Japan, Australia & New Zealand), Latin America (Brazil, Mexico, Argentina) and Middle East and Africa (Saudi Arabia, United Arab Emirates, South Africa).

In our report, we provide 12-15 market players’ information into the report. However, based on the client’s request we will provide additional country and regional market players information as well.


Report

Table Of Content

1. Executive Summary
2. Global Bone Substitutes and Bone Allografts Market Introduction
2.1. Global Bone Substitutes and Bone Allografts Market – Taxonomy
2.2. Global Bone Substitutes and Bone Allografts Market –Definitions
2.2.1. Product
2.2.2. Application
3. Global Bone Substitutes and Bone Allografts Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Global Bone Substitutes and Bone Allografts Market Dynamic Factors – Impact Analysis
3.6. Global Bone Substitutes and Bone Allografts Market – Competition Landscape
4. Global Bone Substitutes and Bone Allografts Market Analysis,2017 – 2021 and Forecast, 2022 – 2028
4.1. Market Analysis,2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
4.2. Year-over-Year (Y-o-Y) Growth Analysis (%)
4.3. Market Opportunity Analysis
5. Global Bone Substitutes and Bone Allografts Market, By Product, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.1. Bone Substitutes
5.1.1. Hydroxyapatites (HAp)
5.1.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.1.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.1.3. Market Opportunity Analysis
5.1.2. Calcium Phosphate
5.1.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.1.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.2.3. Market Opportunity Analysis
5.1.3. Calcium Sulphate
5.1.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.1.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.3.3. Market Opportunity Analysis
5.1.4. Bioactive Glass
5.1.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.1.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.4.3. Market Opportunity Analysis
5.2. Bone Allografts
5.2.1. Freeze Dried
5.2.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.2.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.1.3. Market Opportunity Analysis
5.2.2. Demineralized Bone Matrix
5.2.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.2.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.2.3. Market Opportunity Analysis
5.2.3. Tendon Allografts
5.2.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.2.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.3.3. Market Opportunity Analysis
5.2.4. Synthetic Tendon Grafts
5.2.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
5.2.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.4.3. Market Opportunity Analysis
6. Global Bone Substitutes and Bone Allografts Market, By Application, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.1. Spinal Fusion
6.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.1.3. Market Opportunity Analysis
6.2. Long Bone
6.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.2.3. Market Opportunity Analysis
6.3. Foot and Ankle
6.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.3.3. Market Opportunity Analysis
6.4. Craniomaxillofacial
6.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.4.3. Market Opportunity Analysis
6.5. Joint Reconstruction
6.5.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.5.3. Market Opportunity Analysis
6.6. Dental Bone Grafting
6.6.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.6.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.6.3. Market Opportunity Analysis
6.7. Others
6.7.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
6.7.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.7.3. Market Opportunity Analysis
7. Global Bone Substitutes and Bone Allografts Market Forecast, By Region, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.1. North America
7.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.1.3. Market Opportunity Analysis
7.2. Europe
7.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.2.3. Market Opportunity Analysis
7.3. Asia-Pacific
7.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.3.3. Market Opportunity Analysis
7.4. Latin America
7.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.4.3. Market Opportunity Analysis
7.5. Middle East and Africa
7.5.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
7.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.5.3. Market Opportunity Analysis
7.6. Global Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By Product, Application and Region, 2022 – 2028
8. North America Bone Substitutes and Bone Allografts MarketAnalysis,2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
8.1. By Product Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
8.1.1. Bone Substitutes
8.1.1.1. Hydroxyapatites (HAp)
8.1.1.2. Calcium Phosphate
8.1.1.3. Calcium Sulphate
8.1.1.4. Bioactive Glass
8.1.2. Bone Allografts
8.1.2.1. Freeze Dried
8.1.2.2. Demineralized Bone Matrix
8.1.2.3. Tendon Allografts
8.1.2.4. Synthetic Tendon Grafts
8.2. Application Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
8.2.1.1. Spinal Fusion
8.2.1.2. Long Bone
8.2.1.3. Foot and Ankle
8.2.1.4. Craniomaxillofacial
8.2.1.5. Joint Reconstruction
8.2.1.6. Dental Bone Grafting
8.2.1.7. Others
8.3. Country Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
8.3.1. USA
8.3.2. Canada
8.4. North America Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By  Product, Application, and Country, 2022 – 2028
8.5. North America Bone Substitutes and Bone Allografts Market Dynamics – Trends
9. Europe Bone Substitutes and Bone Allografts Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
9.1. By Product Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
9.1.1. Bone Substitutes
9.1.1.1. Hydroxyapatites (HAp)
9.1.1.2. Calcium Phosphate
9.1.1.3. Calcium Sulphate
9.1.1.4. Bioactive Glass
9.1.2. Bone Allografts
9.1.2.1. Freeze Dried
9.1.2.2. Demineralized Bone Matrix
9.1.2.3. Tendon Allografts
9.1.2.4. Synthetic Tendon Grafts
9.2. Application Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
9.2.1.1. Spinal Fusion
9.2.1.2. Long Bone
9.2.1.3. Foot and Ankle
9.2.1.4. Craniomaxillofacial
9.2.1.5. Joint Reconstruction
9.2.1.6. Dental Bone Grafting
9.2.1.7. Others
9.3. Country Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
9.3.1. Germany
9.3.2. UK
9.3.3. France
9.3.4. Spain
9.3.5. Italy
9.3.6. Russia
9.3.7. Poland
9.3.8. Rest of Europe
9.4. Europe Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By  Product, Application, and Country, 2022 – 2028
9.5. Europe Bone Substitutes and Bone Allografts Market Dynamics – Trends
10. Asia-Pacific Bone Substitutes and Bone Allografts Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
10.1. By Product Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
10.1.1. Bone Substitutes
10.1.1.1. Hydroxyapatites (HAp)
10.1.1.2. Calcium Phosphate
10.1.1.3. Calcium Sulphate
10.1.1.4. Bioactive Glass
10.1.2. Bone Allografts
10.1.2.1. Freeze Dried
10.1.2.2. Demineralized Bone Matrix
10.1.2.3. Tendon Allografts
10.1.2.4. Synthetic Tendon Grafts
10.2. Application Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
10.2.1.1. Spinal Fusion
10.2.1.2. Long Bone
10.2.1.3. Foot and Ankle
10.2.1.4. Craniomaxillofacial
10.2.1.5. Joint Reconstruction
10.2.1.6. Dental Bone Grafting
10.2.1.7. Others
10.3. Country Analysis2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
10.3.1. Japan
10.3.2. China
10.3.3. India
10.3.4. ASEAN
10.3.5. Australia & New Zealand
10.3.6. Rest of Asia-Pacific
10.4. Asia-Pacific Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By  Product, Application, and Country, 2022 – 2028
10.5. Asia-Pacific Bone Substitutes and Bone Allografts Market Dynamics – Trends
11. Latin America Bone Substitutes and Bone Allografts Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
11.1. By Product Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
11.1.1. Bone Substitutes
11.1.1.1. Hydroxyapatites (HAp)
11.1.1.2. Calcium Phosphate
11.1.1.3. Calcium Sulphate
11.1.1.4. Bioactive Glass
11.1.2. Bone Allografts
11.1.2.1. Freeze Dried
11.1.2.2. Demineralized Bone Matrix
11.1.2.3. Tendon Allografts
11.1.2.4. Synthetic Tendon Grafts
11.2. Application Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
11.2.1.1. Spinal Fusion
11.2.1.2. Long Bone
11.2.1.3. Foot and Ankle
11.2.1.4. Craniomaxillofacial
11.2.1.5. Joint Reconstruction
11.2.1.6. Dental Bone Grafting
11.2.1.7. Others
11.3. Country Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
11.3.1. Brazil
11.3.2. Mexico
11.3.3. Argentina
11.3.4. Rest of Latin America
11.4. Latin America Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By  Product, Application, and Country, 2022 – 2028
11.5. Latin America Bone Substitutes and Bone Allografts Market Dynamics – Trends
12. Middle East and Africa Bone Substitutes and Bone Allografts Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn)
12.1. By Product Analysis 2017 – 2021 and Forecast 2022 – 2028by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
12.1.1. Bone Substitutes
12.1.1.1. Hydroxyapatites (HAp)
12.1.1.2. Calcium Phosphate
12.1.1.3. Calcium Sulphate
12.1.1.4. Bioactive Glass
12.1.2. Bone Allografts
12.1.2.1. Freeze Dried
12.1.2.2. Demineralized Bone Matrix
12.1.2.3. Tendon Allografts
12.1.2.4. Synthetic Tendon Grafts
12.2. Application Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
12.2.1.1. Spinal Fusion
12.2.1.2. Long Bone
12.2.1.3. Foot and Ankle
12.2.1.4. Craniomaxillofacial
12.2.1.5. Joint Reconstruction
12.2.1.6. Dental Bone Grafting
12.2.1.7. Others
12.3. Country Analysis 2017 – 2021 and Forecast 2022 – 2028 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
12.3.1. Gulf Cooperation Council (GCC) Countries
12.3.2. Israel
12.3.3. South Africa
12.3.4. Rest of MEA
12.4. MEA Bone Substitutes and Bone Allografts Market – Opportunity Analysis Index, By  Product, Application, and Country, 2022 – 2028
12.5. MEA Bone Substitutes and Bone Allografts Market Dynamics – Trends
13. Competition Landscape 
13.1. Strategic Dashboard of Top Market Players
13.2. Company Profiles (Introduction, Financial Analysis, Technology & Service Offerings, Key Developments, Strategies, and SWOT Analysis)
13.2.1. AlloSource
13.2.2. Baxter
13.2.3. DEPUY SYNTHES
13.2.4. INTEGRA LIFESCIENCES HOLDINGS CORPORATION
13.2.5. Medtronic
13.2.6. NuVasive, Inc.
13.2.7. Orthovita, Inc.
13.2.8. Smith and Nephew Inc.
13.2.9. Stryker Corporation
13.2.10. Wright Medical Group N.V
13.2.11. ZIMMER BIOMET
14. Research Methodology
15. Key Assumptions and Acronyms

Report

Company Profile

  • AlloSource
  • DePuySynthes, Inc.
  • Baxter
  • Nuvasive, Inc.
  • Smith & Nephew
  • Medtronic
  • Orthofix Holdings, Inc.
  • TBF Tissue Engineering
  • OST Development
  • Zimmer Biomet
  • Wright Medical Group N.V.

Description

The bone substitute and allograft bone market is valued at USD 3.1 billion in 2021 and is poised to grow at a significant CAGR of 6.1% over 2022–2028. The growing use of grafts in dental operations is expected to generate profitable growth prospects for the market players during the forecast period. Rising demand for dental bone grafts and technological advances propel the market forward. Increased investment in R&D by key players in bone grafts and their substitutes and an increase in incidences of orthopedic operations among the elderly are projected to generate significant growth for market players over the forecast period. Introducing novel polymer and ceramic materials with biologically superior features is one of the market’s essential developments. New manufacturing technologies like fast prototyping and 3D printing assist in the manufacture of free-form biomaterial scaffolds for tissue regeneration. Furthermore, increased morbidity rates, a growing geriatric population, and an increase in occurrences of osteoarthritis are driving up demand for bone grafts and substitutes. Apart from that, the market is being bolstered by a shift toward minimally invasive procedures and a growing awareness among patients about the benefits of biologic bone regeneration. The availability of improved products in various forms and sizes, the rising frequency of orthopedic difficulties and periodontal disorders, and the growing number of studies examining the enhancement of bioactivity of bone graft substitutes are some of the other growth-inducing aspects. To maintain the market position in the competition, key players worldwide employ various techniques in the bone graft substitutes market. Companies are concentrating on launching sophisticated products and strengthening their distribution channels. Moreover, numerous companies in the global bone graft replacements market are investing in research to develop high-efficiency materials. For instance, in January 2021, Dentsply Sirona acquired Datum Dental Ltd., a company recognized for its unique dental regeneration solutions. Dentsply Sirona promotes the whole OSSIX portfolio in the United States, Canada, and several other countries, including OSSIX Plus, OSSIX Volumax, and OSSIX Bone.

Recent Market Developments:

In January 2020, Orthopeaditrics Corp. introduced a synthetic bone graft substitute in the United States called QuickPack. It is highly viscous and contains calcium phosphate cement that closely resembles the mineral phase of a bone.

In March 2022, Fredun Pharmaceuticals Limited received approval to manufacture Xenografts for various dental and orthopedic surgical appliances from the Central Drugs Standard Control Organisation (COSCO), India.

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