Chronic Refractory Cough Market: By Drug Class, By Route of Administration By End User and Geography

Chronic Refractory Cough Market Size, Share, Growth, Trends, and Global Industry Analysis: By Drug Class (Antibiotics, Decongestants, Corticosteroids, Antihistamines, Acid Blockers, Others), By Route of Administration (Oral, Nasal, Parenteral, and Others) By End User (Hospitals, Clinics, Homecare, Others) and Region

Chronic Refractory Cough Market was valued at US$ 8982.5 million in 2023 and is poised to grow at a CAGR of 4% over 2024-2030. Chronic refractory cough is defined as a cough that persists despite the guideline-based treatment, and key symptoms include a dry irritated cough localized around the laryngeal region, dyspnea, and dysphonia. Based on the drug class, the combination drugs segment is anticipated to dominate the chronic refractory cough market share over the forecast period. According to an article published in the European Respiratory Journal, the overall prevalence of chronic cough was 9.6%. An increase in the prevalence of conditions such as asthma, bronchitis, GERD, and rising awareness among patients are the chronic refractory cough market growth drivers. However, the side effects associated with the drugs for cough could restrict market growth. Advancements and the use of modern techniques in drug development and diagnosis of the disease could act as opportunities for the players in the market

Chronic Refractory Cough Market Key Developments:
  • In June 2022, NeRRe Therapeutics initiated enrolment in a phase-II trial for cough in the USA and UK for Orvepitant.
  • In January 2022, Japan’s MHLW approved Merck’s Gefapixant, a selective P2X3 receptor antagonist for the treatment of adults with refractory chronic cough.

Chronic Refractory Cough Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

4%

Largest Market

North America

Fastest Growing Market

North America

Chronic Refractory Cough Market Dynamics

Due to rising global healthcare spending and disease awareness, the chronic refractory cough market is expected to witness growth. For instance, the launch of pipeline therapies such as Orvepitant Maleate, BLU-5937, Gefapixant, BAY1817080, and S-600918 will contribute to the market expansion in the upcoming years. Thus, the increased awareness, research, and development for chronic respiratory disorders will lead to the growth of the market within the forecast period. However, the reduced approval rate for drugs will have a negative impact on the market growth.

Chronic Refractory Cough Market Segmentation Analysis

Report Benchmarks

Details

Report Study Period

2024-2030

Market Size in 2023

US$ 8982.5 million

Market CAGR

4%

By Drug Class

  • Antibiotics
  • Decongestants
  • Corticosteroids
  • Antihistamines
  • Acid Blockers
  • Others

By Route Of Administration

  • Oral
  • Nasal
  • Parenteral
  • Others

By End User

  • Hospitals
  • Clinics
  • Homecare
  • Others

Key Features of the Report

  • The chronic refractory cough market report provides granular level information about the market size, regional market share, historic market (2019-2023) and forecast (2024-2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

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Frequently Asked Questions

The Chronic Refractory Cough market was valued at US$ 8982.5 million in 2022 and is expected to grow at a 4% CAGR over the forecast period 2023 – 2029.

Advancements and the use of modern techniques in drug development and diagnosis of the disease are the key opportunities for the Chronic Refractory Cough market.

An increase in the prevalence of conditions such as asthma, bronchitis, GERD, and rising awareness among patients are the growth drivers in the Chronic Refractory Cough market.

Merck & Co., GSK PLC, Kyorin Pharmaceuticals, NeRRe Therapeutics, Bayer AG, Shionogi Inc., Avalo Therapeutics, Inc., Aldeyra Therapeutics, Axalbion, and Afferent Pharmaceuticals, Inc. are a few companies operating in the Chronic Refractory Cough market.

Author image

Author

Muni Kumar Meravath

Muni Kumar Meravath is a seasoned Healthcare Market Research Analyst with over 6 years of experience in the healthc.....

1.Executive Summary
2.Global Chronic Refractory Cough Market Introduction 
2.1.Global Chronic Refractory Cough Market  - Taxonomy
2.2.Global Chronic Refractory Cough Market  - Definitions
2.2.1.Drug Class
2.2.2. Route Of Administration
2.2.3.End User
2.2.4.Region
3.Global Chronic Refractory Cough Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Chronic Refractory Cough Market Analysis, 2019 - 2023 and Forecast 2024 - 2030
4.1.  Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Chronic Refractory Cough Market  By Drug Class, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
5.1. Antibiotics
5.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Decongestants
5.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Corticosteroids
5.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Antihistamines
5.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Acid Blockers
5.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
5.6. Others
5.6.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.6.3. Market Opportunity Analysis 
6.Global Chronic Refractory Cough Market  By  Route Of Administration, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
6.1. Oral
6.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Nasal
6.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Parenteral
6.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. Others
6.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
7.Global Chronic Refractory Cough Market  By End User, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
7.1. Hospitals
7.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Clinics
7.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Homecare
7.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Others
7.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
8.Global Chronic Refractory Cough Market  By Region, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Chronic Refractory Cough Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
9.1. Drug Class Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Antibiotics
9.1.2.Decongestants
9.1.3.Corticosteroids
9.1.4.Antihistamines
9.1.5.Acid Blockers
9.1.6.Others
9.2.   Route Of Administration Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Oral
9.2.2.Nasal
9.2.3.Parenteral
9.2.4.Others
9.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Hospitals
9.3.2.Clinics
9.3.3.Homecare
9.3.4.Others
9.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Chronic Refractory Cough Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
10.1. Drug Class Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Antibiotics
10.1.2.Decongestants
10.1.3.Corticosteroids
10.1.4.Antihistamines
10.1.5.Acid Blockers
10.1.6.Others
10.2.   Route Of Administration Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Oral
10.2.2.Nasal
10.2.3.Parenteral
10.2.4.Others
10.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Hospitals
10.3.2.Clinics
10.3.3.Homecare
10.3.4.Others
10.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
11.Asia Pacific (APAC) Chronic Refractory Cough Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
11.1. Drug Class Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Antibiotics
11.1.2.Decongestants
11.1.3.Corticosteroids
11.1.4.Antihistamines
11.1.5.Acid Blockers
11.1.6.Others
11.2.   Route Of Administration Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Oral
11.2.2.Nasal
11.2.3.Parenteral
11.2.4.Others
11.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Hospitals
11.3.2.Clinics
11.3.3.Homecare
11.3.4.Others
11.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Chronic Refractory Cough Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
12.1. Drug Class Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Antibiotics
12.1.2.Decongestants
12.1.3.Corticosteroids
12.1.4.Antihistamines
12.1.5.Acid Blockers
12.1.6.Others
12.2.   Route Of Administration Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Oral
12.2.2.Nasal
12.2.3.Parenteral
12.2.4.Others
12.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Hospitals
12.3.2.Clinics
12.3.3.Homecare
12.3.4.Others
12.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Chronic Refractory Cough Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
13.1. Drug Class Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Antibiotics
13.1.2.Decongestants
13.1.3.Corticosteroids
13.1.4.Antihistamines
13.1.5.Acid Blockers
13.1.6.Others
13.2.   Route Of Administration Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Oral
13.2.2.Nasal
13.2.3.Parenteral
13.2.4.Others
13.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Hospitals
13.3.2.Clinics
13.3.3.Homecare
13.3.4.Others
13.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Merck & Co.
14.2.2.GSK PLC
14.2.3.Kyorin Pharmaceuticals
14.2.4.NeRRe Therapeutics
14.2.5.Bayer AG
14.2.6.Shionogi Inc.
14.2.7.Avalo Therapeutics, Inc.
14.2.8.Aldeyra Therapeutics
14.2.9.Axalbion
14.2.10.Afferent Pharmaceuticals, Inc.
14.2.11.Patara Pharma
15. Research Methodology 
16. Appendix and Abbreviations 

Key Market Players

  • Merck & Co.
  • GSK PLC
  • Kyorin Pharmaceuticals
  • NeRRe Therapeutics
  • Bayer AG
  • Shionogi Inc.
  • Avalo Therapeutics, Inc.
  • Aldeyra Therapeutics
  • Axalbion
  • Afferent Pharmaceuticals, Inc.
  • Patara Pharma

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