Diamond Blackfan Anemia (DBA) Syndrome Market Size, Share, Growth, Trends, and Global Industry Analysis: By Treatment (Corticosteroids, Chelation Therapy, Blood Transfusions, Stem Cell Transplant), By End Users (Hospitals, Clinics) and Region Forecast 2020-2031

Diamond Blackfan Anemia Syndrome Market size was valued at US$ 7,843.9 million in 2023 and is poised to grow at 5.1% CAGR 2024–2030. Diamond-Blackfan Anemia (DBA) Syndrome is a rare and inherited hematologic disorder characterized by an impaired ability of the bone marrow to produce red blood cells, leading to anemia. This condition primarily affects infants and young children, with symptoms often appearing within the first year of life. DBA is caused by genetic mutations that disrupt the production of ribosomal proteins, essential components for protein synthesis and cell growth. Patients with DBA experience symptoms such as fatigue, pale skin, short stature, and developmental abnormalities. DBA is an extremely rare disorder, with an estimated prevalence of 5 to 10 cases per million individuals worldwide.

Diagnosis and treatment of DBA often involve regular blood transfusions, corticosteroids, and, in some cases, stem cell transplantation. Research into the genetic basis of DBA has led to a better understanding of its underlying mechanisms, offering hope for potential targeted therapies in the future. Although most cases are isolated, approximately 45% of people with Diamond-Blackfan anemia inherit the disorder from one of their parents. The increased incidences of diamond-blackfan anemia, burgeoning healthcare expenditure, advancement of therapeutic approaches, soaring federal funding, and surging strategies by government and private organizations to raise illnesses awareness are the aspects that will drive the diamond-blackfan anemia treatment market.

Key Developments

• In July 2021, AstraZeneca procured Alexion Pharmaceuticals, a global biotech company. With this acquisition, the company will be able to enter the market for rare disease medicines, ushering in a new chapter. Moreover, the acquisition strengthened AstraZeneca’s scientific presence in immunology and would allow the company to continue to pioneer the discovery and development of medicines for patients with rare diseases using Alexion’s new complement-biology system and robust pipeline.
• In June 2022, Pfizer will collaborate with Sirana Pharma, a biotechnology company. The collaboration would help Pfizer recognize and validate a novel therapeutic concept for unique and severe bone diseases.