Downstream Processing Market Outlook


Downstream processing is the process of recovery and purification of the biosynthetic products. Biosynthetic products particularly pharmaceuticals, from natural sources such as plant or animal tissue or fermentation broth. Downstream processing may also include recycling of salvageable components and proper treatment of waste. Furthermore, downstream processing is important step in manufacturing of hormones, antibiotics, antibodies, and vaccines. Stages include removal of insoluble, product isolation, product purification, product polishing and few recovery methods may be considered.


Market Dynamics: Global Downstream Processing Market


The market is mainly driven by the rise in R&D investment by the companies and government in the biopharmaceutical industry to produce more effective biopharmaceuticals. In addition, propelling demand for biopharmaceuticals due to the rising prevalence of communicable diseases and chronic diseases such as cancer boosting the market growth over the forecast period. Furthermore, technological developments in purification technology and need for highly pure biopharmaceuticals such as vaccines bolstering the global downstream processing market. However, lack of skilled professionals, high cost of devices and regulatory procedures are expected to hamper the market during the forecast period.


The market is expected to grow at significant rates owing to the rise in demand for biopharmaceutical products. The market is consolidated due to presence of the many companies competing with product innovations and advancements. Companies are focusing on the R&D and new product launches to increase their product portfolio. For instance, in November 2012, Asahi Kasie Medical Co. Ltd. Has launched 5 L QyuSpeed D membrane adsorbers, designed specifically for removal of impurities in bioprocessing. In the product segment, chromatographic columns and resins are expected to have significant growth rate owing to the technological advancements in chromatography techniques and new product launches.


Global downstream processing market is segmented based on product, technique, application, end user and region


Based on the product, the global market is segmented into

  • Membrane Adsorbents
  • Chromatography Columns and Resins
  • Filters
  • Others


Based on technique, the market is segmented into


  • Purification Techniques
    • Gel Chromatography
    • Ion Exchange Chromatography
    • Affinity Chromatography
    • Hydrophobic Interaction Chromatography
    • Solid-Liquid Separation
  • Concentration/Clarification


By application, the market is segmented into

  • Vaccine Production
  • Monoclonal Antibodies Production
  • Insulin Production
  • Erythropoietin Production
  • Immunoglobulin Production
  • Others


By end user, the market is segmented into

  • Biopharmaceutical Manufacturers
  • Contract Manufacturing Organizations
  • Others


By region, the market is segmented into

  • North America
  • Asia Pacific
  • Europe
  • Middle East and Africa
  • Latin America


North America downstream processing market is expected to have major share in market owing to factors such as rise in R&D investment by the companies and government to develop new biopharmaceuticals for communicable diseases and cancer. Europe is expected to expand at unprecedented growth rate owing to presence of key biopharmaceutical companies and significant growth in a number of market players. Asia Pacific is projected to be fastest growing market in global downstream processing market. The growth is attributed to surge in contract manufacturing organizations, increase in company and governments in product developments.


Competitor Analysis

  • Boehringer Ingelheim GmbH (Germany)
  • 3M Company (U.S.)
  • Eppendorf AG (Germany)
  • Danaher Corporation (U.S.)
  • General Electric (U.S.)
  • Finesse Solutions, Inc. (Thermo Fisher Scientific) (U.S.)
  • Merck KGaA (Germany)
  • Lonza Group AG (Switzerland)


Notable Market Developments


  • In August 2015, Danaher Corporation entered into the bioprocessing market by the acquisition of Pall Corporation, a global provider of filtration, separation and purification solutions


Key Features of the Report:

  • The report provides granular level information about the market size, regional market share, historic market (2015-2019) and forecast (2020-2026)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments and startup’s details that are actively working in the market
  • The report provides plethora of information about market entry strategies, regulatory framework and reimbursement scenario
  • The report analyses the impact of socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market



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