- Iodine and Iodides
- Ionic Inhibitors
- Radioactive Iodine
- Beta Blockers
- Thioamides
- Corticosteroids
Graves Orbitopathy Market size is expected to be valued at USD million in 2022, growing at a significant CAGR of x% during 2022–2028. Graves’ ophthalmopathy is also called as thyroid-associated orbitopathy (TAO) and thyroid eye disease (TED), Graves’ orbitopathy (GO) is autoimmune inflammatory disorder of the tissues of periorbit and orbit that is characterized by the retraction of upper eyelid, lagging, swelling and redness of lid, bulging of eyes and conjunctivitis. Most commonly occurs in the individuals having Graves’ disease, and less commonly in the individuals having Hashimoto’s thyroiditis, or in the people with euthyroid. It is a part of systemic process of variable expression in skin, thyroid and eyes that is caused by the autoantibodies which binds to the tissues of these organs. Autoantibodies targets the fibroblasts in the eye muscles and fibroblasts can be differentiated into the fat cells (adipocytes). Muscles and fat cells expands and get inflammation. As per Wickham study in England, in 2016, Graves’ disease is accounted for 0.5 cases per 1000 persons, with high incidence rate in people with age of 40 to 60. Graves’ disease is the high prevalent autoimmune disorder in U.S After Hashimoto thyroiditis. In 2016, as per research study of PREGO (presentation of Graves orbitopathy), incidence of Graves’ orbitopathy in Europe was 10-30/10,000 human annually. However, severity and the incidence of the Graves’ disease in Europe was observed to decline to 2.10/10,000/year. Iodine-131 is used in radioactive iodine ablation (RIA) used to remove whole or a part of thyroid gland, which results in preventing the excessive production of thyroid hormone. Subtotal thyroidectomy used for the removal of thyroid gland is the most invasive treatment option. Key Developments: In September 2014, Avalon Ventures and GlaxoSmithKline plc launced two new companies with US $10 Mn each in series a financing and R&D support companies include Silarus Therapeutics- developing treatments for anaemia and iron overload disorders and Thyritope Biosciences- developing treatments for grave’s orbitopathy Â
Study Period
Base Year
CAGR
Largest Market
Fastest Growing Market
Increase in incidence and prevalence of thyroid disorders, availability of appreciative reimbursement policies for the treatment, and growing awareness regarding the complications related to thyroid disorders are some of the factors driving Graves’ disease market. Side effects associated with drugs are one of the restraints for the graves orbitopathy market.
2021 is the base year and 2028 is the forecast year.
The report covers the five regions and 15+ countries market data: North America (United States, Canada), Europe (Germany, France, Italy, Spain, and United Kingdom (UK), Asia Pacific (China, India, Japan, Australia & New Zealand), Latin America (Brazil, Mexico, Argentina) and Middle East and Africa (Saudi Arabia, United Arab Emirates, South Africa).
In our report, we provide 12-15 market players’ information into the report. However, based on the client’s request we will provide additional country and regional market players information as well.
1. Executive Summary |
2. Global Graves Orbitopathy Market Introduction |
2.1. Global Graves Orbitopathy Market – Taxonomy |
2.2. Global Graves Orbitopathy Market –Definitions |
2.2.1. Drug Class |
2.2.2. Distribution Channel |
3. Global Graves Orbitopathy Market Dynamics |
3.1. Drivers |
3.2. Restraints |
3.3. Opportunities/Unmet Needs of the Market |
3.4. Trends |
3.5. Global Graves Orbitopathy Market Dynamics – Factors Impact Analysis |
3.6. Global Graves Orbitopathy Market – Regulations |
3.6.1. U.S. |
3.6.2. Europe |
3.6.3. Japan |
4. Global Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) |
4.3. Market Oppurtunity Analysis |
5. Global Graves Orbitopathy Market, By Drug Class, 2017 - 2021 and Forecast, 2022 – 2028 |
5.1. Iodine and Iodides |
5.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.1.3. Market Opportunity Analysis |
5.2. Ionic Inhibitors |
5.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.2.3. Market Opportunity Analysis |
5.3. Radioactive Iodine |
5.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.3.3. Market Opportunity Analysis |
5.4. Beta Blockers |
5.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.4.3. Market Opportunity Analysis |
5.5. Thioamides |
5.5.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.5.3. Market Opportunity Analysis |
5.6. Corticosteroids |
5.6.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
5.6.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
5.6.3. Market Opportunity Analysis |
6. Global Graves Orbitopathy Market Forecast, By Distribution Channel, 2017 - 2021 and Forecast, 2022 – 2028 |
6.1. Hospital Pharmacies |
6.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
6.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.1.3. Market Opportunity Analysis |
6.2. Retail Pharmacies |
6.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
6.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.2.3. Market Opportunity Analysis |
6.3. Others |
6.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
6.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
6.3.3. Market Opportunity Analysis |
7. Global Graves Orbitopathy Market Forecast, By Region, 2017 - 2021 and Forecast, 2022 – 2028 |
7.1. North America |
7.1.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
7.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.1.3. Market Opportunity Analysis |
7.2. Europe |
7.2.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
7.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.2.3. Market Opportunity Analysis |
7.3. Asia-Pacific |
7.3.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
7.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.3.3. Market Opportunity Analysis |
7.4. Latin America |
7.4.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
7.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.4.3. Market Opportunity Analysis |
7.5. Middle East and Africa |
7.5.1. Market Analysis, 2017 – 2021 and Forecast, 2022 – 2028 (Revenue, USD Mn) |
7.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
7.5.3. Market Opportunity Analysis |
7.6. Global Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel, and Region, 2022 – 2028 |
8. North America Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
8.1. Drug Class Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
8.1.1. Iodine and Iodides |
8.1.2. Ionic Inhibitors |
8.1.3. Radioactive Iodine |
8.1.4. Beta Blockers |
8.1.5. Thioamides |
8.1.6. Corticosteroids |
8.2. Distribution Channel Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
8.2.1. Hospital Pharmacies |
8.2.2. Retail Pharmacies |
8.2.3. Others |
8.3. Country Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%) |
8.3.1. U.S. |
8.3.2. Canada |
8.4. North America Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel, and Country, 2022 – 2028 |
8.5. North America Graves Orbitopathy Market Dynamics – Trends |
9. Europe Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
9.1. Drug Class Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
9.1.1. Iodine and Iodides |
9.1.2. Ionic Inhibitors |
9.1.3. Radioactive Iodine |
9.1.4. Beta Blockers |
9.1.5. Thioamides |
9.1.6. Corticosteroids |
9.2. Distribution Channel Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
9.2.1. Hospital Pharmacies |
9.2.2. Retail Pharmacies |
9.2.3. Others |
9.3. Country Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
9.3.1. Germany |
9.3.2. UK |
9.3.3. France |
9.3.4. Spain |
9.3.5. Italy |
9.3.6. Russia |
9.3.7. Poland |
9.3.8. Rest of Europe |
9.4. Europe Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel and Country, 2022 – 2028 |
9.5. Europe Graves Orbitopathy Market Dynamics – Trends |
10. Asia-Pacific Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
10.1. Drug Class Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
10.1.1. Iodine and Iodides |
10.1.2. Ionic Inhibitors |
10.1.3. Radioactive Iodine |
10.1.4. Beta Blockers |
10.1.5. Thioamides |
10.1.6. Corticosteroids |
10.2. Distribution Channel Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
10.2.1. Hospital Pharmacies |
10.2.2. Retail Pharmacies |
10.2.3. Others |
10.3. Country Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), |
Y-o-Y Growth (%), and Market Share (%) |
10.3.1. Japan |
10.3.2. China |
10.3.3. India |
10.3.4. ASEAN |
10.3.5. Australia & New Zealand |
10.3.6. Rest of Asia-Pacific |
10.4. Asia-Pacific Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel and Country, 2022 – 2028 |
10.5. Asia-Pacific Graves Orbitopathy Market Dynamics – Trends |
11. Latin America Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
11.1. Drug Class Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
11.1.1. Iodine and Iodides |
11.1.2. Ionic Inhibitors |
11.1.3. Radioactive Iodine |
11.1.4. Beta Blockers |
11.1.5. Thioamides |
11.1.6. Corticosteroids |
11.2. Distribution Channel Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
11.2.1. Hospital Pharmacies |
11.2.2. Retail Pharmacies |
11.2.3. Others |
11.3. Country Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
11.3.1. Brazil |
11.3.2. Mexico |
11.3.3. Argentina |
11.3.4. Venezuela |
11.3.5. Rest of Latin America |
11.4. Latin America Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel and Country, 2022 – 2028 |
11.5. Latin America Graves Orbitopathy Market Dynamics – Trends |
12. Middle East and Africa Graves Orbitopathy Market Analysis, 2017 - 2021 and Forecast, 2022 – 2028 |
12.1. Drug Class Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
12.1.1. Iodine and Iodides |
12.1.2. Ionic Inhibitors |
12.1.3. Radioactive Iodine |
12.1.4. Beta Blockers |
12.1.5. Thioamides |
12.1.6. Corticosteroids |
12.2. Distribution Channel Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%) |
12.2.1. Hospital Pharmacies |
12.2.2. Retail Pharmacies |
12.2.3. Others |
12.3. Country Analysis (2017 – 2021) and Forecast (2022 – 2028) by Revenue (USD Mn), Y-o-Y Growth (%), and Market Share (%) |
12.3.1. Gulf Cooperation Council (GCC) Countries |
12.3.2. Israel |
12.3.3. South Africa |
12.3.4. Rest of MEA |
12.4. MEA Graves Orbitopathy Market - Opportunity Analysis Index, By Drug Class, By Distribution Channel and Country, 2022 – 2028 |
12.5. MEA Graves Orbitopathy Market Dynamics – Trends |
13. Competition Landscape |
13.1. Strategic Dashboard of Top Market Players |
13.2. Company Profiles (Introduction, Financial Analysis, Drug Class & Service Offerings, Key Developments, Strategies, and SWOT Analysis) |
13.2.1. Abbott Laboratories (U.S.) |
13.2.2. Alimera Sciences (U.S.) |
13.2.3. Allergan plc (Ireland.) |
13.2.4. Ampio Pharmaceuticals. (U.S.) |
13.2.5. Bayer AG (Germany) |
13.2.6. F. Hoffmann-La Roche (Switzerland) |
13.2.7. Novartis AG (Switzerland) |
13.2.8. Pfizer Inc. (U.S.) |
13.2.9. Regeneron Pharmaceuticals Inc. (U.S.) |
13.2.10. Valeant (Canada) |
14. Research Methodology |
15. Key Assumptions and Acronyms |