Spider are the venomous animals with an estimated of approximately 100,000 extant species. Spider venoms are complex cocktails composed of various compounds such as salts, peptides, small organic molecules, and proteins. Peptides are the primary components of spider venoms, and some species produce venom containing >1000 unique peptides of mass 2–8 kDa. The progress of the spider venom business has been aided by continuous innovative work to develop novel medications and treatments for creature or creepy crawly stings. The biotechnology and medical services industries are attracting a lot of attention from emerging economies all around the world. The interest in anti-venom treatment, which is the only licenced treatment for snake chomp with no alternative, is a major element driving the growth of the spider venom industry. Infringement of backwoods lands for horticultural and lodging purposes has enabled humans to remain in close proximity to toxic creepy crawlies and wildlife, resulting in an increase in the prevalence of venomous nibbles. The high prevalence of scorpion bites, snake bites, and other creature or bug bites, such as fish stings, are all factors that encourage the growth of the spider venom market.