Lipid Nanoparticles (LNP) Market: By Type (Solid Lipid Nanoparticles (SLN), Nanostructured Lipid Carriers (NLC), and Others), By Product (mRNA, siRNA, Plasmid DNA, and Others), By Application (Vaccines & Drugs, and Scientific Research) and Geography

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Lipid Nanoparticles (LNP) Market size was valued at USD  906.6 million in 2022 and is poised to grow at a significant CAGR of 6.6% over 2023-29. Nanoparticles have received interest recently because of their potential role in efficient medication delivery. LNPs are now widely recognized in the pharmaceutical and biotechnology sectors as a cutting-edge, commercially successful delivery system enabling the unheard-of commercialization of gene treatments. As a result, LNPs have ushered in a new era of medicine that allows for the effective treatment or cure of genetic illnesses and the production of vaccines within the body rather than through the purification of non-infectious viruses.

Lipid nanoparticles offer several important characteristics over widely used lipid-based nucleic acid delivery systems such as:

  • High nucleic acid encapsulation efficiency and potent transfection
  • Improved penetration into tissues to deliver therapeutics
  • Low cytotoxicity and immunogenicity
  • Targeted Therapy
  • Escape from the endosomes

For the creation of therapeutic products for protein replacement therapy, preventive or curative vaccinations, and gene editing, LNP-based formulations provide significant prospects. LNP-based formulations are increasingly being considered for use across a variety of other application areas, including anticancer agents and antibiotics, peptide and protein-based synthetic vaccines, ligand targeted formulations, and imaging contrast agents, in addition to RNA, DNA, and siRNA-based therapeutics. LNPs are anticipated to facilitate the creation of ever more sophisticated nanomedicines during the next ten years. Examples include the design of synthetic vaccines, immunotherapies, and drug combination products when LNP-based formulations are necessary to guarantee the co-presentation of various components into the target cell. Personalized or custom formulations that can enable results like the insertion of tumor-associated neoantigens into mRNA vaccines are another opportunity that can be achieved by combining LNPs with tissue sequencing and other valuable technologies.

Lipid Nanoparticles (LNP) Market Key Developments:
  • In February 2021, Merck KGaA announced the extension of its strategic partnership with BioNTech to accelerate the supply of urgently needed lipids and increase the quantities to be delivered in 2021. The lipids were used for the production of the Pfizer-BioNTech Covid-19 vaccine.
  • On 6th February 2023, Croda (Avanti) offering lipid nanoparticles to the cosmetics and agrobusiness customers. To strengthen its presence in the cosmetics and pharmaceuticals, company has acquired the  Solus Biotech, leader in the biotechnology-derived active ingredients for beauty care and pharmaceuticals. Solus Biotech acquisition provides Croda, to access their R&D hub in the Asia Pacific region and also it brings portfolio of phospholipids.
  • On 6th July 2020, Croda’s acquired Avanti Polar Lipids to strengthen its Nucleic Acid Delivery platform, which is a technology area that focuses on lipid-based drug delivery systems that carry nucleic acid material.
  • On 9th September 2022, WuXi STA opened a new sterile lipid nanoparticle formulation facility at its Wuxi city campus owing to increase in demand for the complex injectables and lipid nanoparticles. This facility will help the company to enhance global CDMO services for its customers. This new facility integrates multi-channel chip, micro-mixer system, and complex preparation system into a multi-channel micro-mixer core LNP manufacturing platform, offering significant advantages in drug-loading, liposome particle size control, and encapsulation efficiency.  In addition, the modular design provides greater processing flexibility, enabling this platform to serve a wide range of manufacturing scales from 10-50 L per batch. manufacturing capacity of ingredients for lipid systems used in novel therapeutic drugs, such as mRNA vaccines.  In line with the company’s strategy to ‘Empower Biologics Delivery,’ Croda will also invest up to $58 million, bringing the total project investment to up to $133 million.
  • On 9th August 2023, AstraZeneca entered into an agreement with CanSino Biologics, will use its mRNA manufacturing platform to support AZ on the R&D of certain vaccines. In May 2020, CanSino Biologics signed a deal with the Precision NanoSystems to develop an mRNA lipid nanoparticle vaccine.

Lipid Nanoparticles Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

6.6%

Largest Market

North America

Fastest Growing Market

Asia Pacific
Lipid Nanoparticles (LNP) Market Dynamics

Due to their use as the ideal delivery method for various messenger RNA (mRNA)-based vaccination candidates being developed for the prevention of COVID-19, lipid nanoparticles (LNPs) have recently attracted much attention. Over approximately 30 years of commercial use, lipid nanoparticles' capacity to encapsulate genetic material, including mRNA, and a variety of other biologically active substances, for regulated delivery to a target cell or organ site has been clinically demonstrated. LNPs have a long history of successful use in clinical settings and can be quickly created and scaled up into a final product, making them the de facto standard for gene- and cell-based therapies and other nanomedicines. Regulatory agencies and organizations and high production and R&D costs may restraints the market growth.

Key Features of the Reports

  • The report provides granular level information about the market size, regional market share, historic market (2019-2023), and forecast (2024-2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Lipid Nanoparticles Market Segmentation

By Type
  • Solid Lipid Nanoparticles (SLN),
  • Nanostructured Lipid Carriers (NLC), and
  • Others
By Product Type
  • mRNA,
  • siRNA,
  • Plasmid DNA
  • Others
By Application
  • Vaccines &
  • Drugs, and
  • Scientific Research

Frequently Asked Questions

The lipid nanoparticles (lnp) market size was valued at USD 906.6 million in 2022 and is poised to grow at a significant CAGR of 6.6% over 2023-29

Croda, NOF Corporation, Evonik, Merck KGaA, Lipoid, and Genevant Sciences are some of the major market players in the Lipid Nanoparticles Market.

Asia Pacific is the fastest-growing region for lipid nanoparticles (lnp) market

1. Executive Summary
2.  Global Lipid Nanoparticles (LNP) Market Introduction 
2.1. Global Lipid Nanoparticles (LNP) Market  - Taxonomy
2.2. Global Lipid Nanoparticles (LNP) Market  - Definitions
2.2.1. By Type
2.2.2. By Product
2.2.3. By Application
2.2.4.  By Country
3. Global Lipid Nanoparticles (LNP) Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Key Developments
4. Global Lipid Nanoparticles (LNP) Market  By Type, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
4.1. Solid Lipid Nanoparticles (SLN)
4.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
4.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
4.1.3. Market Opportunity Analysis 
4.2. Nanostructured Lipid Carriers (NLC)
4.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
4.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
4.2.3. Market Opportunity Analysis 
4.3. Others
4.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
4.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
4.3.3. Market Opportunity Analysis 
5. Global Lipid Nanoparticles (LNP) Market  By Product, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
5.1. mRNA
5 1 1  Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. siRNA
5.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Plasmid DNA
5.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Others
5.4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
6. Global Lipid Nanoparticles (LNP) Market  By Application, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
6.1. Vaccines & Drugs
6.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Scientific Research
6.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
7.  Global Lipid Nanoparticles (LNP) Market  By Region, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
7.1. North America
7.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Europe
7.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Asia Pacific
7.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Latin America
7.4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
7.5. MEA
7.5.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million)
7.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.5.3. Market Opportunity Analysis 
7.6.  Global Lipid Nanoparticles (LNP) Market - Opportunity Analysis Index, By Product, Type, Application, and Region, 2023-2029
8. North America Lipid Nanoparticles (LNP) Market, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
8.1. Type Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.1.1. Solid Lipid Nanoparticles (SLN)
8.1.2. Nanostructured Lipid Carriers (NLC)
8.1.3. Others
8.2. Product Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.2.1. mRNA
8.2.2. siRNA
8.2.3. Plasmid DNA
8.2.4. Others
8.3. Application Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.3.1. Vaccines & Drugs
8.3.2. Scientific Research
8.4. Country Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.4.1. USA
8.4.2. Canada
9. Europe Lipid Nanoparticles (LNP) Market, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
9.1. Type Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1. Solid Lipid Nanoparticles (SLN)
9.1.2. Nanostructured Lipid Carriers (NLC)
9.1.3. Others
9.2. Product Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1. mRNA
9.2.2. siRNA
9.2.3. Plasmid DNA
9.2.4. Others
9.3. Application Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1. Vaccines & Drugs
9.3.2. Scientific Research
9.4. Country Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1. Germany
9.4.2. UK
9.4.3. France
9.4.4. Italy
9.4.5. Spain
9.4.6. Rest of Europe
10. Asia Pacific Lipid Nanoparticles (LNP) Market, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
10.1. Type Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1. Solid Lipid Nanoparticles (SLN)
10.1.2. Nanostructured Lipid Carriers (NLC)
10.1.3. Others
10.2. Product Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1. mRNA
10.2.2. siRNA
10.2.3. Plasmid DNA
10.2.4. Others
10.3. Application Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1. Vaccines & Drugs
10.3.2. Scientific Research
10.4. Country Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1. China 
10.4.2. ANZ 
10.4.3. Japan
10.4.4. Rest of APAC
11. Latin America Lipid Nanoparticles (LNP) Market, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
11.1. Type Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1. Solid Lipid Nanoparticles (SLN)
11.1.2. Nanostructured Lipid Carriers (NLC)
11.1.3. Others
11.2. Product Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1. mRNA
11.2.2. siRNA
11.2.3. Plasmid DNA
11.2.4. Others
11.3. Application Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1. Vaccines & Drugs
11.3.2. Scientific Research
11.4. Country Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1. Brazil
11.4.2. Mexico
11.4.3. Rest of LA
12. MEA Lipid Nanoparticles (LNP) Market, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million)
12.1. Type Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1. Solid Lipid Nanoparticles (SLN)
12.1.2. Nanostructured Lipid Carriers (NLC)
12.1.3. Others
12.2. Product Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1. mRNA
12.2.2. siRNA
12.2.3. Plasmid DNA
12.2.4. Others
12.3. Application Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1. Vaccines & Drugs
12.3.2. Scientific Research
12.4. Country Analysis,  2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1. GCC Countries
12.4.2. South Africa
12.4.3. Rest of MEA
13.  Competition Landscape
13.1. Strategic Dashboard of Top Market Players
13.2. Company Profiles (Introduction, Financial Analysis, By Product Offerings, Key Developments, Strategies, and SWOT Analysis)
13.2.1. Evonik
13.2.2. Merck KGaA
13.2.3. Genevant Sciences
13.2.4. Croda International Plc
13.2.5. Lipoid
13.2.6. FUJIFILM Corporation
13.2.7. Corden Pharma GmbH
13.2.8. PolyPeptide
13.2.9. Polypeptide Therapeutic Solutions (PTS)
13.2.10. Phosphorex Inc
13.2.11. Samsung Biologics
13.2.12. Precision NanoSystems Inc. (Danaher Corporation) 
13.2.13. NOF Corporation 
13.2.14. Nippon Fine Chemical
14.  Research Methodology
15.  Key Assumptions and Acronyms
Figure 01: Global Lipid Nanoparticles Market Value (USD Million), 2018 - 2029
Figure 02: Overview of the Global Lipid Nanoparticles Market share (%), By Type, 2022
Figure 03: Overview of the Global Lipid Nanoparticles Market Value, By Product, 2022
Figure 04: Overview of the Global Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 05: Global Lipid Nanoparticles Market Share by Type, 2023 and 2029
Figure 06: Global Lipid Nanoparticles Market Y-o-Y Growth (%), by Type, 2024-2029
Figure 07: Global Lipid Nanoparticles Market, Historical, Forecast Market Sizes (USD Million) and Market Opportunity (USD Million), by Type, 2018, 2023, & 2029 
Figure 08: Global Lipid Nanoparticles Market Share by Product, 2023 and 2029
Figure 09: Global Lipid Nanoparticles Market Y-o-Y Growth (%), by Product, 2024-2029
Figure 10: Global Lipid Nanoparticles Market, Historical, Forecast Market Sizes (USD Million) and Market Opportunity (USD Million), by Product, 2018, 2023, & 2029 
Figure 11: Global Lipid Nanoparticles Market Share by Application, 2023 and 2029
Figure 12: Global Lipid Nanoparticles Market Y-o-Y Growth (%), by Application, 2024-2029
Figure 13: Global Lipid Nanoparticles Market, Historical, Forecast Market Sizes (USD Million) and Market Opportunity (USD Million), by Application, 2018, 2023, & 2029 
Figure 14: Global Lipid Nanoparticles Market Share by Region, 2023 and 2029
Figure 15: Global Lipid Nanoparticles Market Y-o-Y Growth (%), by Region, 2024-2029
Figure 16: Global Lipid Nanoparticles Market, Historical, Forecast Market Sizes (USD Million) and Market Opportunity (USD Million), by Region, 2018, 2023, & 2029 
Figure 17: North America Lipid Nanoparticles Market Value (USD ‘Million), 2018 - 2029
Figure 18: North America Lipid Nanoparticles Market Value (USD Million), 2018, 2022 & 2029
Figure 19: North America Lipid Nanoparticles Market Value (USD Million), By Type, 2022
Figure 20: North America Lipid Nanoparticles Market Value (USD Million), By Product, 2022
Figure 21: Overview of North America Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 22: Europe Lipid Nanoparticles Market Value (USD ‘Million), 2018 - 2029
Figure 23: Europe Lipid Nanoparticles Market Value (USD Million), 2018, 2022 & 2029
Figure 24: Overview of Europe Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 25: Europe Lipid Nanoparticles Market Value (USD Million), By Type, 2022
Figure 26: Europe Lipid Nanoparticles Market Value (USD Million), By Product, 2022
Figure 27: Asia Pacific Lipid Nanoparticles Market Value (USD ‘Million), 2018 - 2029
Figure 28: Asia Pacific Lipid Nanoparticles Market Value (USD Million), 2018, 2022 & 2029
Figure 29: Asia Pacific Lipid Nanoparticles Market Value (USD Million), By Type, 2022
Figure 31: Overview of Asia Pacific Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 30: Asia Pacific Lipid Nanoparticles Market Value (USD Million), By Product, 2022
Figure 32: Latin America Lipid Nanoparticles Market Value (USD ‘Million), 2018 - 2029
Figure 33: Latin America Lipid Nanoparticles Market Value (USD Million), 2018, 2022 & 2029
Figure 34: Latin America Lipid Nanoparticles Market Value (USD Million), By Type, 2022
Figure 35: Overview of Latin America Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 36: Latin America Lipid Nanoparticles Market Value (USD Million), By Product, 2022
Figure 37: MEA Lipid Nanoparticles Market Value (USD ‘Million), 2018 - 2029
Figure 38: MEA Lipid Nanoparticles Market Value (USD Million), 2018, 2022 & 2029
Figure 39: MEA Lipid Nanoparticles Market Value (USD Million), By Type, 2022
Figure 40: Overview of MEA Lipid Nanoparticles Market Value (USD Million), By Application, 2022
Figure 41: MEA Lipid Nanoparticles Market Value (USD Million), By Product, 2022
  • Evonik
  • Merck KGaA
  • Genevant Sciences
  • Croda International Plc
  • Lipoid
  • FUJIFILM Corporation
  • Corden Pharma GmbH
  • PolyPeptide
  • Polypeptide Therapeutic Solutions (PTS)
  • Phosphorex Inc
  • Samsung Biologics
  • Precision NanoSystems Inc. (Danaher Corporation)
  • NOF Corporation
  • Nippon Fine Chemical

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