Marginal Zone Lymphoma Treatment Market: By Drug ), Imbruvica, Umbralisib, Revlimid, Rituximab, Venetoclax, Cladribine, Carfilzomib, and Others), By Distribution Channel, and Region Forecast 2019-2030

Marginal Zone Lymphoma Treatment Market Size, Share, Growth, Trends, and Global Industry Analysis: By Drug (Brukinsa (Zanubrutinib)), Imbruvica (Ibrutinib), Umbralisib (Ukoniq), Revlimid (Lenalidomide), Rituximab (Rituxan), Venetoclax, Cladribine, Carfilzomib, and Others), By Distribution Channel (Retail Pharmacy, and Hospital Pharmacy), and Region Forecast 2019-2030

Marginal Zone Lymphoma Treatment Market size was valued at US$ 2.91 billion in 2023, and is poised to grow at a CAGR of 6.3% CAGR from 2024 to 2030. Marginal zone lymphoma is a slow-growing B-cell non-Hodgkin lymphoma that begins forming from certain areas of lymph tissue. There are three regions from where it begins such as the spleen, lymph nodes, and lymphoid tissue that contain a lot of B-cells. In some people, H. pylori infection can lead to the development of marginal zone lymphoma. The exact mechanism by which H. pylori infection causes marginal zone lymphoma is not fully understood, but it is thought to involve the production of inflammatory cytokines by the bacteria. The risk increases in a person of 65+ years of age with a weakened immune system. The prevalence of MZL is estimated to be about 2 cases per 100,000 people. The mortality rate for MZL is about 5%. All these numerical data indicated the prospect of the Marginal Zone Lymphoma (MZL) Treatment Market in the forecast period.

There are several FDA-approved drugs available for the treatment of MZL. These drugs include Rituximab (Rituxan), Lenalidomide (Revlimid), Ibrutinib (Imbruvica), Zanubrutinib (Brukinsa). These drugs can be used to treat MZL in a variety of settings, including newly diagnosed MZL, relapsed or refractory MZL, and MZL that has spread to other parts of the body. The drug sales for MZL drugs are significant. In 2021, the global sales of MZL drugs were estimated to be over $1.5 billion. The United States and Europe are the two largest markets for MZL drugs. The FDA and the EU have approved a number of drugs for the treatment of MZL. These approvals are based on the results of clinical trials that have shown that these drugs can improve the survival and quality of life of patients with Marginal Zone Lymphoma (MZL).

Marginal Zone Lymphoma Treatment Market Key Developments

  • In February 2021, The U.S. Food and Drug Administration (FDA) announced the approval of UKONIQ™ (umbralisib), a once-daily, oral medication for the treatment of marginal zone lymphoma (MZL) that has returned or worsened following prior treatment with an anti-CD20 antibody.

Marginal Zone Lymphoma Treatment Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

6.3%

Largest Market

Europe

Fastest Growing Market

North America

Marginal Zone Lymphoma Treatment Market Dynamics

The approved drugs market in MZL is expected to grow at a   of 6.3% from 2023 to 2029. This growth in the Marginal Zone Lymphoma (MZL) Pharma Market is driven by the increasing prevalence of MZL, the availability of new and effective drugs, and the growing demand for personalized medicine. Several medications have received approval from the FDA and the EU for treating Marginal Zone Lymphoma (MZL) Disease. These approvals are based on clinical trial findings indicating these medications can increase patients with MZL's chances of survival and quality of life. These advancements in disease management and its prognosis through various research activities would ultimately drive the MZL treatment molecule sales as confirmatory results will bring more patients into the treatment option.

Personalized treatment options for marginal zone lymphoma (MZL) are based on several factors, including the stage of the disease, the patient's age and overall health, and the specific genetic mutations present in the lymphoma cells. Personalized medicine can be used to identify the best treatment options for each patient. This is important because MZL is a heterogeneous disease, and different patients may respond differently to different treatments. Thus, increased preference for personalized medicine is expected to boost the Marginal Zone Lymphoma (MZL) Market Opportunity.

Marginal Zone Lymphoma Treatment Market Segmentation Analysis

Report Benchmarks

Details

Report Study Period

2024-2030

Market Size in 2023

US$ 2.91 billion

Market CAGR

6.3%

By Drug Type

  • Brukinsa (Zanubrutinib)
  • Imbruvica (Ibrutinib)
  • Umbralisib (Ukoniq)
  • Revlimid (Lenalidomide)
  • Rituximab (Rituxan)
  • Venetoclax
  • Cladribine
  • Carfilzomib
  • Others

By Distribution Channel

  • Retail Stores
  • Hospital Pharmacy

By Region

  • North America
  • Europe
  • The Asia Pacific
  • Latin America
  • MEA

Key Features of the Report

  • The marginal zone lymphoma treatment market report provides granular level information about the market size, regional market share, historic market (2019 to 2023) and forecast (2024 to 2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments and startup’s details that are actively working in the market
  • The report provides plethora of information about market entry strategies, regulatory framework and reimbursement scenario
  • The report analyses the impact of socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market

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Frequently Asked Questions

The global marginal zone lymphoma treatment market size was valued at US$ 2.59 billion in 2023, and is growing at a CAGR of 6.3% CAGR from 2024 to 2030.

The leading players in the Market are Incyte Corporation, InnoCare Pharma, ENTEROME SA, Beijing Mabworks Biotech Co., Ltd., ADC Therapeutics, MEI Pharma, Inc., Genentech, Inc., Incyte Corporation, Novartis, AstraZeneca, Roche, Oncternal Therapeutics, Inc, Celgene, IGM Biosciences, Inc., Loxo Oncology, Genmab, ArQule, Sound Biologics, Adicet Bio, Inc, Celldex Therapeutics, TG Therapeutics, Velos Bio Inc., Newave Pharmaceutical Inc., among others

Historic years considered for the market study are 2018 through 2022, 2022 is considered as the base year for market estimation, and Seven years forecast is presented from 2023 – 2029.

Author image

Author

Muni Kumar Meravath

Muni Kumar Meravath is a seasoned Healthcare Market Research Analyst with over 6 years of experience in the healthc.....

1. Executive Summary
2. Global Marginal Zone Lymphoma Treatment Market Introduction 
2.1.Global Marginal Zone Lymphoma Treatment Market  - Taxonomy
2.2.Global Marginal Zone Lymphoma Treatment Market  - Definitions
2.2.1.Drug Type
2.2.2.Distribution Channel
2.2.3.Region
3. Global Marginal Zone Lymphoma Treatment Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4. Global Marginal Zone Lymphoma Treatment Market Analysis, 2019-2023 and Forecast 2024-2030
4.1.  Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5. Global Marginal Zone Lymphoma Treatment Market  By Drug Type, 2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
5.1. Brukinsa (Zanubrutinib)
5.1.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Imbruvica (Ibrutinib)
5.2.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Umbralisib (Ukoniq)
5.3.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Revlimid (Lenalidomide)
5.4.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Rituximab (Rituxan)
5.5.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
5.6. Venetoclax
5.6.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.6.3. Market Opportunity Analysis 
5.7. Cladribine
5.7.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.7.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.7.3. Market Opportunity Analysis 
5.8. Carfilzomib
5.8.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.8.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.8.3. Market Opportunity Analysis 
5.9. Others
5.9.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
5.9.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.9.3. Market Opportunity Analysis 
6. Global Marginal Zone Lymphoma Treatment Market  By Distribution Channel, 2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
6.1. Retail Stores
6.1.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Hospital Pharmacy
6.2.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
7. Global Marginal Zone Lymphoma Treatment Market  By Region, 2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
7.1. North America
7.1.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Europe
7.2.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Asia Pacific (APAC)
7.3.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Middle East and Africa (MEA)
7.4.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
7.5. Latin America
7.5.1. Market Analysis, 2019-2023 and Forecast, 2024-2030, (Sales Value USD Million)
7.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.5.3. Market Opportunity Analysis 
8. North America Marginal Zone Lymphoma Treatment Market ,2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
8.1. Drug Type Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.1.1.Brukinsa (Zanubrutinib)
8.1.2.Imbruvica (Ibrutinib)
8.1.3.Umbralisib (Ukoniq)
8.1.4.Revlimid (Lenalidomide)
8.1.5.Rituximab (Rituxan)
8.1.6.Venetoclax
8.1.7.Cladribine
8.1.8.Carfilzomib
8.1.9.Others
8.2.  Distribution Channel Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.2.1.Retail Stores
8.2.2.Hospital Pharmacy
8.3.  Country Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
8.3.1.United States of America (USA)
8.3.2.Canada
9. Europe Marginal Zone Lymphoma Treatment Market ,2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
9.1. Drug Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Brukinsa (Zanubrutinib)
9.1.2.Imbruvica (Ibrutinib)
9.1.3.Umbralisib (Ukoniq)
9.1.4.Revlimid (Lenalidomide)
9.1.5.Rituximab (Rituxan)
9.1.6.Venetoclax
9.1.7.Cladribine
9.1.8.Carfilzomib
9.1.9.Others
9.2.  Distribution Channel Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Retail Stores
9.2.2.Hospital Pharmacy
9.3.  Country Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Germany
9.3.2.France
9.3.3.Italy
9.3.4.United Kingdom (UK)
9.3.5.Spain
9.3.6.Rest of EU
10. Asia Pacific (APAC) Marginal Zone Lymphoma Treatment Market ,2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
10.1. Drug Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Brukinsa (Zanubrutinib)
10.1.2.Imbruvica (Ibrutinib)
10.1.3.Umbralisib (Ukoniq)
10.1.4.Revlimid (Lenalidomide)
10.1.5.Rituximab (Rituxan)
10.1.6.Venetoclax
10.1.7.Cladribine
10.1.8.Carfilzomib
10.1.9.Others
10.2.  Distribution Channel Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Retail Stores
10.2.2.Hospital Pharmacy
10.3.  Country Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.China
10.3.2.India
10.3.3.Australia and New Zealand (ANZ)
10.3.4.Japan
10.3.5.Rest of APAC
11. Middle East and Africa (MEA) Marginal Zone Lymphoma Treatment Market ,2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
11.1. Drug Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Brukinsa (Zanubrutinib)
11.1.2.Imbruvica (Ibrutinib)
11.1.3.Umbralisib (Ukoniq)
11.1.4.Revlimid (Lenalidomide)
11.1.5.Rituximab (Rituxan)
11.1.6.Venetoclax
11.1.7.Cladribine
11.1.8.Carfilzomib
11.1.9.Others
11.2.  Distribution Channel Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Retail Stores
11.2.2.Hospital Pharmacy
11.3.  Country Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.GCC Countries
11.3.2.South Africa
11.3.3.Rest of MEA
12. Latin America Marginal Zone Lymphoma Treatment Market ,2019-2023 and Forecast 2024-2030 (Sales Value USD Million)
12.1. Drug Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Brukinsa (Zanubrutinib)
12.1.2.Imbruvica (Ibrutinib)
12.1.3.Umbralisib (Ukoniq)
12.1.4.Revlimid (Lenalidomide)
12.1.5.Rituximab (Rituxan)
12.1.6.Venetoclax
12.1.7.Cladribine
12.1.8.Carfilzomib
12.1.9.Others
12.2.  Distribution Channel Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Retail Stores
12.2.2.Hospital Pharmacy
12.3.  Country Analysis 2019-2023 and Forecast 2024-2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Brazil
12.3.2.Mexico
12.3.3.Rest of LA
13. Competition Landscape
13.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
13.2.1.AbbVie
13.2.2.Genentech
13.2.3.Johnson & Johnson
13.2.4.Novartis
13.2.5.Pfizer
13.2.6.Teva Pharmaceuticals
14. Research Methodology 
15. Appendix and Abbreviations 

Key Market Players

  • Incyte Corporation
  • InnoCare Pharma
  • ENTEROME SA
  • Beijing Mabworks Biotech Co. Ltd.
  • ADC Therapeutics
  • MEI Pharma Inc.
  • Genentech Inc.
  • Incyte Corporation
  • Novartis
  • AstraZeneca
  • Kite Pharma
  • Roche
  • Oncternal Therapeutics Inc.
  • Celgene
  • IGM Biosciences
  • Loxo Oncology
  • Genmab
  • Sound Biologics
  • Adicet Bio
  • Celldex Therapeutics
  • Newave Pharmaceutical

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