Multi Specific Antibodies Market: By Type (Bispecific Antibody, Tri specific Antibody, Tetra specific Antibody, Multi Specific Antibody), By Drug– (Multispecific (Amivantamab, Blinatumomab), Bispecific (Glofitamab, Epcoritamab, Mosunetuzumab, Teclistamab, Faricimab, Tebentafusp, Emicizumab)), By Indication (Autoimmune Disorders, Genetic Disorders, Haematological Malignancies, Ophthalmic Disorders, Skin Cancers, Solid Tumours), By End User (Hospital, Pharmacies, Others) and Geography    

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Multi-Specific Antibodies Market size was valued at USD 5.6 billion in 2023 and is poised to grow at 9.5% CAGR over the forecast period from 2024 to 2030. Driven by the rising interest in R&D activities and growing need for effective medicines, the multi-specific antibody therapies market in terms of therapeutic areas, the market is expected to be driven by medications that treat cancer The rising incidence of chronic diseases, such as oncological disorders, autoimmune disorders, and infectious diseases, is expected to create demand for Multi specific antibody therapies. Such therapies offer a promising approach since they target many disease pathways at the same timeframe. Currently, two multi specific antibodies are under development to treat haematological malignancies and non-small cell lung cancer.

On March 1, 2024, Janssen Biotech, Inc., received FDA approval for amivantamab-vmjw (Rybrevant) with carboplatin and pemetrexed as a first-line treatment for locally advanced or metastatic non-small cell lung cancer. Antibody engineering has been a key driver of the multi-specific antibody business. In recent years, immense progress has been achieved in the development of novel antibody formats and engineering approaches that allow to produce Multi specific antibodies with increased efficacy and stability. For example, breakthroughs in recombinant DNA technology and protein engineering have enabled the development of bispecific antibodies with enhanced pharmacokinetics, less immunogenicity, and higher tumour penetration. The newest prospects in the Multi specific antibody market are primarily driven by increased demand for targeted and personalized medicines, as well as the advent of novel multi specific antibody formats and technologies. The increasing interest in novel Multi specific antibody formats and technology represents a significant opportunity for the multi specific antibody market.

Multi Specific Antibodies Market Key Developments:
  • On March 1, 2024, Janssen Biotech, Inc received FDA approval for amivantamab-vmjw (Rybrevant) with carboplatin and pemetrexed as a first-line treatment for locally advanced or metastatic non-small cell lung cancer.
  • On June 15, 2023, The FDA has approved Genentech's Columvi (Glofitamab), the first and only bispecific antibody with a fixed duration treatment for people with relapsed or refractory diffuse large B-cell lymphoma.

Multi Specific Antibodies Market Summary

Study Period

2024 - 2030

Base Year

2023

CAGR

9.5%

Largest Market

North America

Fastest Growing Market

Asia Pacific
Multi-Specific Antibodies Market Dynamics

The Multi-Specific Antibodies Market is being driven by the ongoing discovery and expansion of therapeutic applications for multi specific antibodies (MsAbs) beyond oncology. MsAbs' versatility in treating autoimmune illnesses, infectious diseases, and other therapeutic areas expected to drive the market. Continuous advances in antibody engineering, including novel forms and superior designs, boost the therapeutic potential and efficacy of MsAbs. These technological discoveries are propelling the creation of next-generation MsAbs with increased specificity and decreased immunogenicity. Growing investment in biopharmaceutical R&D benefits the MsAbs market. Pharmaceutical corporations, investors, and research institutions provide funding to MsAbs activities, stimulating innovation and hastening their progression from preclinical to clinical applications. However, technical hurdles in MsAb development, such as establishing optimal binding affinity and stability, are a danger. Immunogenicity concerns, such as possible immunological reactions to MsAbs, may restrict their clinical efficacy and pose safety risks. The high costs and extended delays associated with MsAbs development pose a considerable challenge. High R&D costs, along with the unpredictability of clinical trial success, can be a barrier to market entry and sustainability for some companies. Additionally Stringent regulatory criteria for multi-specific antibody approval pose a concern. Delays in regulatory processes, uncertainty about data needs, and the possibility of unforeseen regulatory hurdles may delay the timely commercialization of MsAbs. The opportunity lies in the research and development of combination treatments that include MsAbs. Customizing treatment procedures and pursuing personalized medicine tactics provide opportunities to address specific patient populations while boosting treatment efficacy and Market. Therefore, Multi-Specific Antibodies Market stands to capitalize on this trend, driving continued growth and innovation within the industry.

Key Features of the Reports

  • The report provides granular level information about the market size, regional market share, historic market (2019-2023), and forecast (2024-2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Multi Specific Antibodies Market Segmentation

By Type
  • Bispecific Antibody
  • Tri specific Antibody
  • Tetra specific Antibody
  • Multi Specific Antibody
By Indication
  • Autoimmune Disorders
  • Genetic Disorders
  • Haematological Malignancies
  • Ophthalmic Disorders
  • Skin Cancers
  • Solid Tumours
By End User
  • Hospital
  • Pharmacies
  • Others

Frequently Asked Questions

Multi-Specific Antibodies Market size was valued at USD 5.6 billion in 2023 and is poised to grow at 9.5% CAGR over the forecast period from 2024 to 2030.

The rising incidence of cancer and autoimmune illnesses is driving the market for multi specific antibodies. These diseases continue to be a large unmet medical need, and the development of new and effective treatments is critical to improve patient outcomes.

The latest trend in the multispecific antibody market is primarily driven by the growing need for targeted and personalized therapeutics, as well as the rise of novel multispecific antibody formats and technologies.

Market research is segmented based on based on type, drug, indication, end user and region.

North America is estimated to dominate with the highest CAGR over the forecast period.

1.Executive Summary
2.Global Multi Specific Antibodies Market Introduction 
2.1.Global Multi Specific Antibodies Market  - Taxonomy
2.2.Global Multi Specific Antibodies Market  - Definitions
2.2.1.Type 
2.2.2.Indication 
2.2.3.End User
2.2.4.Region
3.Global Multi Specific Antibodies Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Multi Specific Antibodies Market Analysis, 2019 - 2023 and Forecast 2024 - 2030
4.1.  Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Multi Specific Antibodies Market  By Type , 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
5.1. Bispecific Antibody
5.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Tri specific Antibody
5.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Tetra specific Antibody
5.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Multi Specific Antibody
5.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
6.Global Multi Specific Antibodies Market  By Indication , 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
6.1. Autoimmune Disorders
6.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Genetic Disorders
6.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Haematological Malignancies
6.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. Ophthalmic Disorders
6.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
6.5. Skin Cancers
6.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.5.3. Market Opportunity Analysis 
6.6. Solid Tumours
6.6.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.6.3. Market Opportunity Analysis 
7.Global Multi Specific Antibodies Market  By End User, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
7.1. Hospital
7.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Pharmacies
7.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Others
7.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
8.Global Multi Specific Antibodies Market  By Region, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Multi Specific Antibodies Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
9.1. Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Bispecific Antibody
9.1.2.Tri specific Antibody
9.1.3.Tetra specific Antibody
9.1.4.Multi Specific Antibody
9.2.  Indication  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Autoimmune Disorders
9.2.2.Genetic Disorders
9.2.3.Haematological Malignancies
9.2.4.Ophthalmic Disorders
9.2.5.Skin Cancers
9.2.6.Solid Tumours
9.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Hospital
9.3.2.Pharmacies
9.3.3.Others
9.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Multi Specific Antibodies Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
10.1. Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Bispecific Antibody
10.1.2.Tri specific Antibody
10.1.3.Tetra specific Antibody
10.1.4.Multi Specific Antibody
10.2.  Indication  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Autoimmune Disorders
10.2.2.Genetic Disorders
10.2.3.Haematological Malignancies
10.2.4.Ophthalmic Disorders
10.2.5.Skin Cancers
10.2.6.Solid Tumours
10.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Hospital
10.3.2.Pharmacies
10.3.3.Others
10.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
11.Asia Pacific (APAC) Multi Specific Antibodies Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
11.1. Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Bispecific Antibody
11.1.2.Tri specific Antibody
11.1.3.Tetra specific Antibody
11.1.4.Multi Specific Antibody
11.2.  Indication  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Autoimmune Disorders
11.2.2.Genetic Disorders
11.2.3.Haematological Malignancies
11.2.4.Ophthalmic Disorders
11.2.5.Skin Cancers
11.2.6.Solid Tumours
11.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Hospital
11.3.2.Pharmacies
11.3.3.Others
11.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Multi Specific Antibodies Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
12.1. Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Bispecific Antibody
12.1.2.Tri specific Antibody
12.1.3.Tetra specific Antibody
12.1.4.Multi Specific Antibody
12.2.  Indication  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Autoimmune Disorders
12.2.2.Genetic Disorders
12.2.3.Haematological Malignancies
12.2.4.Ophthalmic Disorders
12.2.5.Skin Cancers
12.2.6.Solid Tumours
12.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Hospital
12.3.2.Pharmacies
12.3.3.Others
12.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Multi Specific Antibodies Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
13.1. Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Bispecific Antibody
13.1.2.Tri specific Antibody
13.1.3.Tetra specific Antibody
13.1.4.Multi Specific Antibody
13.2.  Indication  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Autoimmune Disorders
13.2.2.Genetic Disorders
13.2.3.Haematological Malignancies
13.2.4.Ophthalmic Disorders
13.2.5.Skin Cancers
13.2.6.Solid Tumours
13.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Hospital
13.3.2.Pharmacies
13.3.3.Others
13.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Sonafi S.A.
14.2.2.AbbVie Inc.
14.2.3.Pfizer Inc.
14.2.4.Johnson & Johnson
14.2.5.Portola Pharmaceuticals
14.2.6.Bristol-Myers Squibb
14.2.7.Sino Biologics
14.2.8.Roche Holding AG
14.2.9.Amgen Inc.
14.2.10.Novartis AG
14.2.11.Merck & Co. Inc.
14.2.12.Regeneron Pharmaceuticals Inc.
15. Research Methodology 
16. Appendix and Abbreviations 
  • Sonafi S.A.
  • AbbVie Inc.
  • Pfizer Inc.
  • Johnson & Johnson
  • Portola Pharmaceuticals
  • Bristol-Myers Squibb
  • Sino Biologics
  • Roche Holding AG
  • Amgen Inc.
  • Novartis AG
  • Merck & Co. Inc.
  • Regeneron Pharmaceuticals Inc.
  • Genentech Inc.
  • Eli Lilly and Company
  • Takeda Pharmaceutical Company Limited
  • MorphoSys AG
  • Xencor Inc.
  • Gilead Sciences Inc.
  • AstraZeneca plc
  • Ganymed Pharmaceuticals
  • OncoMed Pharmaceuticals
  • Bayer AG
  • Daiichi Sankyo Company Limited

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