Myelofibrosis Disease Pipeline Drugs Assessment Clinical Trails Analysis, Player Profiles, Collaborations, Key Targets, Geographic Focus, and Data Publications, 2019 - 2030

Myelofibrosis is a rare bone marrow disorder, affects the production of the blood cells.This results in extensive scarring of bone marrow and maylead to severe fatigue, anemia, weakness, and sometimes enlargement of spleen. Myelofibrosis belong the group of diseases known as myeloproliferative disorders. During initial stages of the disease, symptoms may not appear.But after the progression of disease due to disruption of blood cell production increases the symptoms such as tiredness, shortness of breath, bone pain and others.

Diagnosis includes blood tests for determining the blood cell count, imaging techniques such as X-ray and MRI. Bone marrow biopsy may be done to confirm the diagnosis of myelofibrosis. Genetic testing may be done for the gene mutations responsible for the myelofibrosis. Immediate treatment usually not require if symptoms didn’t appear. Generally treatment is to reduce the symptoms. Treatment that targets gene mutation may be given. Ruxolitinib is only drug that approved to treat myelofibrosis.