The global Needle Free Drug Delivery Market size was valued at USD 7.41 billion in 2020. It is poised to exhibit a CAGR of 10.6% during the forecast period 2021-2027. Needle Free Drug Delivery Market is the medical devices that deliver the drug through the skin using the forces such as shock waves, pressurized gas or electrophoresis and by Lorentz which propels the drug through the skin which virtually nullify the use of the hypodermic needles. Large number of the patients opting for self-administration of drugs which would be possible using the needle free drug delivery devices. The adoption of the needle free drug delivery devices helps in reducing the healthcare expenses to the patients. In recent years, needle-free injection technologies, such as injection systems that deliver medications subcutaneously without piercing the skin with a needle, have gained popularity around the world. Needle anxiety, injection-related pain, needlestick injuries, and infection and/or disease transfer have all been reduced using needle-free injection devices. Over the last few decades, huge strides have been achieved in the development of safe, effective, and convenient medication administration methods. The latest generation of needle-free drug delivery systems reduces the incidence of needle stick injuries among healthcare workers and prevents syringe and needle misuse. Needles-free technology has the obvious advantage of successful drug delivery for a wide range of medications and is bio-equivalent to a syringe and needle, resulting in less pain, and it is strongly preferred by patients. In comparison to conventional needles, the injection is much faster, and there are no needle disposal difficulties. Not only may it help the pharmaceutical sector enhance product sales, but it also has the potential to improve dose regimen compliance and outcomes. A portal device, on the other hand, injects a quick, high-pressure stream of medicine into the skin in programmable amounts, as thin as a strand of hair.