Global Orthobiologics Market: By Product Type (Viscosupplementation Products, Allografts, Synthetic Orthobiologics, DBM (Demineralized Bone Matrix ),BMP (Bone Morphogenetic Proteins), PRP (Platelet-Rich Plasma), and BAMC, By Application (Osteoarthritis and Degenerative Arthritis, Spinal Fusion, Fracture Recovery, Soft Tissue Injuries, Maxillofacial and Dental Applications), By End User (Hospitals, Research and Academic Institutes, Dental Clinics and Facilities), and Geography


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The global orthobiologics market was valued at $5261.38 million in 2021 and is projected to reach $7208.11 million by 2028, registering a CAGR of 4.6% from 2022 to 2028. Orthobiologics are biological substances that are used to help injuries to heal more quickly. Orthobiologics are used to improve the healing of injured muscles, fractures, tendons, and ligaments. Orthobiologics are made from substances that occur naturally in the body. When they are used in more amounts, they may help to increase the healing process. When a tissue is injured bleeding occurs, after bleeding matrix, stem cells and growth factors play an important role in tissue healing and they are natural orthobiologics in human body. Matrix serves as building blocks that help to fill tissue gaps. Growth factors act on stem cells to cause the repair of the injured tissue. The rise in the global geriatric population, which is more susceptible to diseases like osteoarthritis and others, is fueling the expansion of the orthobiologics market. Other factors projected to drive market growth include increased awareness of orthobiologics and increased demand for improved therapy. Furthermore, during the projected period, strong development potential in developing countries and an increase in demand for sophisticated treatment are expected to generate new possibilities for market competitors. However, the market's expansion is hampered by the greater cost of orthobiologics and the lengthy approval process.Because of the rising prevalence of OA, a better understanding of the disease pathophysiology, improved early detection, disease prevention strategies, and early management are all urgently needed. Orthobiologics may be one such treatment option for OA.

Orthobiologics Market Summary

Study Period


Base Year




Largest Market

North America

Fastest Growing Market

Asia Pacific

Sports related injuries are common among professional and recreational athletes are increasingly encountered and diagnosed. They demand quick healing so that they can return to their normal sporting activities. Hence, orthobiologics is gaining more preference from various physicians. Bone grafts act by their osteoinductive, osteoconductive and osteogenic properties to stimulate new bone formation and have no effect on the healing of muscles, tendons and ligaments. On the other hand, autologous blood, PRP and autologous conditioned serum deliver growth factors to the diseased areas to stimulate the repair process. These biologic substances have their own advantages and some disadvantages also. Lack of clinical data and cost-intensive products are restrain the growth of the market. On the other hand, the high cost associated with orthobiologics-based treatments is the major factor restraining the growth of the orthobiologics market.

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  • The report provides granular level information about the market size, regional market share, historic market (2018 to 2022) and forecast (2023 to 2029)
  • The report covers in-detail insights about the competitors overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
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  • The report analyses the impact of socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market

Orthobiologics Market Segmentation

Product Type
  • Viscosupplementation Products
  • Allografts
  • Synthetic Orthobiologics
  • DBM (Demineralized Bone Matrix )
  • BMP (Bone Morphogenetic Proteins)
  • PRP (Platelet-Rich Plasma)
  • Others
  • Maxillofacial and Dental Applications
  • Osteoarthritis and Degenerative Arthritis
  • Soft Tissue Injuries
  • Spinal Fusion
  • Fracture Recovery
End User
  • Hospitals
  • Research and Academic Institutes
  • Dental Clinics and Facilities

Frequently Asked Questions

2021 is the base year and 2028 is the forecast year.

The report covers the five regions and 15+ countries market data: North America (United States, Canada), Europe (Germany, France, Italy, Spain, and United Kingdom (UK), Asia Pacific (China, India, Japan, Australia & New Zealand), Latin America (Brazil, Mexico, Argentina) and Middle East and Africa (Saudi Arabia, United Arab Emirates, South Africa).

In our report, we provide 12-15 market players’ information into the report. However, based on the client’s request we will provide additional country and regional market players information as well.

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  • Medtronic
  • NuVasive Inc.,
  • Stryker Corporation
  • Zimmer Biomet
  • Orthofix International
  • RTI Surgical Inc.,
  • Kuros Biosciences Ltd
  • Bioventus LLC
  • DePuy Synthes (Johnson and Johnson)
  • Arthrex
  • SeaSpine Holdings Corporation