Skin Replacement Market Size, Share, Growth, Trends, and Global Industry Analysis: By Graft Type (Auto-grafts, Allografts, Xenografts, and Synthetic Skin), By Indication Type (Burns, Ulcers, and Others), By End User (Hospitals, Dermal Wound Clinics, and Others), and Region Forecast 2020-2031

Skin Replacement Market size was valued at US$ 1,030.6 million in 2024 and is expected to reach US$ 1,539.5 million by 2031, growing at a significant CAGR of 5.9% from 2025-2031. The increased prevalence of dermatological illnesses is a primary driver of the market's demand. Another major element driving the market share is the growing number of burn victims.

According to World Health Organization studies, most of the 180,000 global deaths attributable to burn injuries each year occur in low and middle-income nations. Globally increasing life expectancy rate and advancement in skin replacement technology and increasing spending on healthcare is expected to be the key growth driver for the market during the study period. The development of artificial skin replacement goods has made significant progress. Continued research indicates that the market for skin replacement products will grow, and each new product appears to carve out its position in the field. Increased life expectancy, rising disposable income, and favorable demographics contribute to the worldwide market's rise. Over the projected period, the worldwide market is expected to benefit from an increase in approvals for novel skin treatment procedures.

Furthermore, prominent players' increased focus on research and development operations is expected to boost market expansion in the future. Based on graft type, the auto-grafts segment accounted for the largest market share in 2021, and the market for the same segment is anticipated to grow faster at the highest rate during the forecast period. The market growth for the auto-grafts segment can be attributed to the wide use of autografts for treating open burns and wounds.

Key Developments

• In Feb 2022  AVITA Medical, Inc. a regenerative medicine company announced that the United States Food and Drug Administration (FDA) has reviewed and approved the premarket approval application (PMA) supplement for RECELL Autologous Cell Harvesting Device, an enhanced RECELL System aimed at providing clinicians a more efficient user experience and simplified workflow. The RECELL System is a device that enables healthcare professionals to produce a suspension of Spray-On Skin Cells using a small sample of the patient's own skin for the treatment of acute thermal burns.  
• In April 2021, MedSkin Solutions Dr. Suwelack AG expanded its MatriDerm portfolio with the launch of MatriDerm Flex Dermal Matrix and MatriDermFenestrated Dermal Matrix. MatriDerm is a single-use three-dimensional acellular dermal matrix composed of bovine collagen fibers and bovine elastin.