Tooth Regeneration Market Size, Share, Growth, Trends, and Global Industry Analysis: By Application (Dentin, Pulp, Enamel), By Demographics (Geriatric, Adults, Middle-Aged, Others), By End-User (Hospitals, Dental Clinics, Others), and Region Forecast 2020-2031

Tooth Regeneration Market size was valued at US$ 4.3 million in 2024 and is expected to reach US$ 6.7 billion by 2031, growing at a significant CAGR of 6.5% from 2025-2031. Tooth regeneration is the evolutionary invention in tissue regeneration techniques. Tooth regeneration is referred to as the manipulation of non-dental and dental adult stem cells to engineer biological teeth (dentin, enamel, pulp). These stem cells can be taken from a patient and grown in the laboratory and replace the missing tooth, where they may continue to grow and integrate into the oral environment. Tooth regenerative techniques may include stem cells or lasers.

The global market is mainly driven by the worldwide prevalence of dental problems and research and development activities towards innovative techniques for tooth loss problems. In addition, favorable reimbursement policies such as coverage of Medicaid insurance for dental loss treatment and the emergence of new technologies such as laser tooth generation techniques are expected to boost the global tooth generation market during the forecast period. Furthermore, tooth regeneration technologies have significant advantages over other alternatives. 

Key Developments

• In June 2024, Kyoto City-based Toregem Biopharma announced that it is developing the world's first tooth regeneration drug. Clinical and safety trials are scheduled to begin in September 2024, followed by another clinical trial for individuals with congenital edentulism, a condition characterized by the absence of some teeth at birth. The company aims to commercialize this technology by 2030.
• In December 2023, the European Federation of Periodontology (EFP) announced Dentsply Sirona as its new sponsor. The regenerative product division of Dentsply Sirona, the world's largest manufacturer of professional dental products and technologies, partnered with the EFP. This sponsorship agreement, finalized in the last quarter of 2023, will support the EFP in expanding its activities and enhancing its oral health prevention campaigns, ultimately benefiting both dental professionals and the general public.