The global tooth regeneration market size valued US$ 1487.8 million in 2021 and expected to reach US$ 1998.7 million by 2028, at a CAGR of 4.9% during forecast period 2022-2028. Tooth regeneration is the evolutionary invention in tissue regeneration techniques. Tooth regeneration is referred as the manipulating non-dental and dental adult stem cells to engineer biological teeth (dentin, enamel, pulp). These stem cells can be taken from a patient and grown them in the laboratory and replace the missing tooth, where it may continue to grow and integrate into oral environment. Tooth regenerative technique may include stem cells or laser. Global tooth regeneration market is mainly driven by the worldwide prevalence of the dental problems and research and development activities towards innovative techniques to tooth loss problems. In addition, favourable reimbursement policies such as coverage of Medicaid insurance for dental loss treatment and emergence of new technologies such as laser tooth generation techniques are expected to boost the global tooth generation market during the forecast period. Furthermore, tooth regeneration technologies have significant advantages over the other alternatives.  However, a high cost of the procedures and regulatory approval issues are expected to hamper the growth of the market over the forecast period. Key developments:  In March 2016, U.S. FDA has approved “True Regeneration” by Millennium Dental Technologies, the world’s first full-mouth true periodontal regeneration.